CHATER 7: Chromosomes, chromatin, and the nucleosome 1. What is the cost (challenge)of compaction of DNA into chromosome? 2. How the challenge could be resolved? 3. What are the advantage of the challenge?
1. What is the cost (challenge) of compaction of DNA into chromosome? 2. How the challenge could be resolved? 3. What are the advantage of the challenge? CHAPTER 7: Chromosomes, chromatin, and the nucleosome
CHATER 7: Chromosomes, chromatin, and the nucleosome OUTLINE Chromosome sequence diversity Chromosome duplication segregation The nucleosome Higher-order chromatin structure Regulation of chromatin structure Nucleosome assembly
OUTLINE ➢ Chromosome sequence & diversity ➢ Chromosome duplication & segregation ➢ The nucleosome ➢ Higher-order chromatin structure ➢ Regulation of chromatin structure ➢ Nucleosome assembly CHAPTER 7: Chromosomes, chromatin, and the nucleosome
CHATER 7: Chromosomes, chromatin, and the nucleosome Chromosome sequence diversity Chromosomes Shape: circular or linear Number in an organism is characteristic Copy: haploid, diploid polyploid Genomes 3/15/05
Chromosome sequence & diversity CHAPTER 7: Chromosomes, chromatin, and the nucleosome Chromosomes ➢ Shape: circular or linear ➢ Number in an organism is characteristic ➢ Copy: haploid, diploid, polyploid Genomes 3/15/05
n Difference in the structures of 5 eukarya otic and prokaryotic cells a is a key to better understand the molecular processes of genome maintenance and expression, as well as the differences in these processes between eukaryotes and prokaryotes 3/15/05
Difference in the structures of eukaryotic and prokaryotic cells is a key to better understand the molecular processes of genome maintenance and expression, as well as the differences in these processes between eukaryotes and prokaryotes Chromosome sequence & diversity 3/15/05
b haploid Figure 7 bacteria 30030∽0 flagellum capsule nucleoid chromosom plasmid prokaryotic cell diploid cell 1 um apparatus eukaryotic cell nucleus- UT chromosomes endoplasmic 10 um reticulum mitochondria haploid cell bright o 2004 Pearson Education, Inc, publishing as Benjamin Cum
Chromosome sequence & diversity Figure 7-1*