The B Cell Immune DefenseInterleukin-1ANInvadingmicrobeHelperT cellTcellMemorycellreceptor-MHCproteinAntigerProcessedantigenMacrophageHelper T cellProcessedPlasmacellPlasmacellantigen:lnterleukin-2cell-1B cell receptor(antibody)BcellAntibody-Microbemarkedfordestruction
6
C.NK cell （natural killer)ActionofNaturalKillerCellonTarget CellKiller cellPerforinVesicleCellmembraneTarget cellNucleus
C. NK cell（natural killer） 7
### ii.Mononuclear phagocyte system(ornposed of the cells that are derived frommonocytes in blood and as meanwhile have highcapabilitytophagocytosebloodmonocyteCT,lymphoid Tmacrophagelungdust cellliverKupffer cellbonetissueosteoclastnervetissuemicrogliaepidermisLangerhans cell8
### ii. Mononuclear phagocyte system (MPS)### blood monocyte CT,lymphoid T macrophage lung dust cell Composed of the cells that are derived from monocytes in blood and as meanwhile have high capability to phagocytose. 8 lung dust cell liver Kupffer cell bone tissue osteoclast nerve tissue microglia epidermis Langerhans cell
###ili.Antigen-presentingcells(APC)###HowAntigens Are Presented-MHCproteincaptureAntigenprocessantigeh-presentMHC-IIBody cellForeignmicrobeProcessedAg-MHCll co.antigenmacrophagesurfacAntigen-presenting cellTlymphocytes9
capture process antigen present ### iii. Antigen-presenting cells (APC)### 9 present MHC-II Ag-MHCII co. macrophage surface T lymphocytes immune
Constitution:a. dendritic cell:·Blood DC·Langerhans cellinterstitialcellveiledcell·interdigitating cellfollicular dendriticcellsb.macrophage:10MPS
Constitution: a. dendritic cell: •Blood DC •Langerhans cell •interstitial cell 10 •veiled cell •interdigitating cell follicular dendritic cells b. macrophage: MPS