Estimated tB incidence rates. 2013 Estimated new TB cases(all forms) pe 100000 popul 10-19 20-49 125-299 Not applicable 5/3/2016 Mycobacteria-Junqi's Lecture for 16 MD students
5/3/2016 Mycobacteria -Junqi's Lecture for MD students 16
Estimated HIv prevalence in new and relapse TB cases, 2013 5-19 2049 No da The boundaries and names shown and the used on this map do not imply the expression of ata Source: Global Tuberculosis eport 2014. WHO, 2014 World Health y Organization Dotted and dashed lines on maps represent te border lines for which there may not yet be full agreement. WHO 2014. All rights reserved 5/3/2016 Mycobacteria- Jungi's Lecture for 17 MD students
5/3/2016 Mycobacteria -Junqi's Lecture for MD students 17
结核的感染过程 M tuberculosis M.bovs(型结核杆菌 M tuberculosis complex(MTBC)1 M. Africanum(洲结核菌) M. Canetti(卡氏结核杆菌) M. microti(田鼠结核杆菌) 5/3/2016 Mycobacteria-Junqi's Lecture for 18 MD students
5/3/2016 Mycobacteria-Junqi's Lecture for MD students 18 M. tuberculosis complex (MTBC) M. tuberculosis M. bovis(牛型结核杆菌) M. Africanum（非洲结核杆菌） M. Canetti（卡氏结核杆菌） M. microti （田鼠结核杆菌） 结核的感染过程
Spread of beijing clade of M. tuberculosis Medscape www.medscape.com RUSSIA UNITED STATES Percent Beij ing strain 275% ON 5I 5074% AUSTRALIA 1024% 19% Percent of TB due to Beijing strains based on spoligotypes Antaresia Source: Emerg Infect Dis e 2002 Centers for Disease Control and Prevention(CDC) 5/3/2016 Mycobacteria-Junqi's Lecture for 19 MD students
5/3/2016 Mycobacteria-Junqi's Lecture for MD students 19 Spread of Beijing clade of M. tuberculosis
TB主要生物学性状: 结核杆菌细胞 结构革兰阳 内层:肽聚糖 外层:脂质(60%) Polypeptides(e. g, PPD) ee lipids(e vaxes mycos G+:1~4 Arabinogalactan— G-:11~22 蛋白质 Cytoplasm 多糖 5/3/2016 Mycobacteria s lecture for MD students
5/3/2016 Mycobacteria-Junqi's Lecture for MD students 20 TB主要生物学性状： 1 .结核杆菌细胞 壁结构与革兰阳 性菌相似： 内层：肽聚糖 外层：脂质（60％） G+:1~4% G-:11~22% 蛋白质 多糖