Helicobacter pylori(幽门螺杆菌) 角产 C Helicobacter pylori is a spiral-shaped gram negative rod .H. pylori consists of a large diversity of strains, and the genomes of three have been completely sequenced 8 H pylori is associated with antral gastritis 窦炎), duodenal( peptic) ulcer disease(十二指 肠溃疡), gastric ulcers(胃溃疡), and gastric carcinoma(胃癌)和MALT(胃粘膜相关B细胞 淋巴瘤) 5/3/2016 Helicobacter pylori-Junqi's Lecture for md students
5/3/2016 Helicobacter pylori-Junqi's Lecture for MD students 1 Helicobacter pylori (幽门螺杆菌) Helicobacter pylori is a spiral-shaped gramnegative rod H. pylori consists of a large diversity of strains, and the genomes of three have been completely sequenced H.pylori is associated with antral gastritis（胃 窦炎）, duodenal (peptic) ulcer disease（十二指 肠溃疡）, gastric ulcers（胃溃疡）, and gastric carcinoma（胃癌）和MALT（胃粘膜相关B细胞 淋巴瘤）
Helicobacter pylori, Hp 今1982 Warren和 Marshal)分离出“ unidentified curved bacilli ☆1984 Langenberg等命名为“ campylobacter- like organism,CLO” ☆1988 Thompson等发现其16 SrRNA序列分析相似于 Wolinella属” ☆1989G00dwin等发现5个分类学特征,命名“Hp” 幽门螺杆菌位于: 8-变形菌纲 (Epsilonproteobacteria) 螺杆菌科 helicobacterace)) 弯曲菌目( Campylobacterale 螺杆菌属( helicobacter) 5/3/2016 Helicobacter pylori-Junqi's Lecture for md students
5/3/2016 Helicobacter pylori-Junqi's Lecture for MD students 2 Helicobacter pylori，Hp 1982 Warren和Marshall分离出“unidentified curved bacilli” 1984 Langenberg等命名为“campylobacter- like organism, CLO” 1988 Thompson等发现其16S rRNA序列分析相似于Wolinella属” 1989 Goodwin等发现5个分类学特征，命名 “Hp” 幽门螺杆菌位于： ε-变形菌纲 （Epsilonproteobacteria） 弯曲菌目（Campylobacterales） 螺杆菌科Helicobacteraceae） 螺杆菌属（Helicobacter）
In 2005 the Karolinska Institute in Stockholm awarded the nobel prize in Physiology or Medicine to Marshall and Robin Warren, his long-time collaborator, for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulce er disease 5/3/2016 Helicobacter pylori-Junqi's Lecture for md students
5/3/2016 Helicobacter pylori-Junqi's Lecture for MD students 3 In 2005, the Karolinska Institute in Stockholm awarded the Nobel Prize in Physiology or Medicine to Marshall and Robin Warren, his long-time collaborator, "for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease
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5/3/2016 Helicobacter pylori -Junqi's Lecture for MD students 4
生物学性状 今 x,、等醒 ◇革兰染色阴性螺旋弯曲形,细菌常排列成S形或海鸥状。 ◇一端带有2一6根鞭毛,运动活泼 ◆在胃黏膜上皮表面,胃小凹内 及腺腔内,呈不均匀的集团状 分布 5/3/2016 Helicobacter pylori-Junqi's Lecture for md students
5/3/2016 Helicobacter pylori-Junqi's Lecture for MD students 5 生物学性状 革兰染色阴性螺旋弯曲形，细菌常排列成S形或海鸥状。 一端带有2－6根鞭毛，运动活泼 在胃黏膜上皮表面，胃小凹内 及腺腔内，呈不均匀的集团状 分布