Controlled drug release >History The modern era of controlled release can be traced to the development of the first commercially successful oral sustained-release products in the late 1940s and early 1950s, and to the development of controlled release of marine antifoulants from rubber in the 1950s. Delivery of drugs by means of controlled release technology began in the 1970s and came about various mechanism controlled in the 1980s
17 ¾History • The modern era of controlled release can be traced to the development of the first commercially successful oral sustained-release products in the late 1940s and early 1950s, and to the development of controlled release of marine antifoulants from rubber in the 1950s. • Delivery of drugs by means of controlled release technology began in the 1970s and came about various mechanism controlled in the 1980s. Controlled drug release Controlled drug release
Controlled drug release (Cont) History People began to study the intelligent controlled release technology in the 1990s.Then it has continued to expand so rapidly that there are now numerous products both on the market and in development
18 ¾ History • People began to study the intelligent controlled release technology in the 1990s. Then it has continued to expand so rapidly that there are now numerous products both on the market and in development. Controlled drug release Controlled drug release (Cont.) (Cont.)
Controlled drug release (Cont) >Advantages This technology enable drugs to be more effective From an economic viewpoint,such optimized formulations can lead to reduced hospital stays and additional savings to health services
19 ¾Advantages • This technology enable drugs to be more effective • From an economic viewpoint, such optimized From an economic viewpoint, such optimized formulations can lead to reduced hospital stays and formulations can lead to reduced hospital stays and additional savings to health services. additional savings to health services. Controlled drug release Controlled drug release (Cont.) (Cont.)