游充通大皇 氯丙嗪(chlorpromazine) Shanghai Jiao Tong University CH
Shanghai Jiao Tong University 氯丙嗪（chlorpromazine）
上浒文通大学 后 Shanghai Jiao Tong University 1949.4, French navy surgeon Laborit, studied anti-shock drug promethazine(异丙嗪)，partial success 1950,chlorpromazine anti-shock;temperature decrease;quiet
Shanghai Jiao Tong University 1949.4，French navy surgeon Laborit, studied anti-shock drug promethazine （异丙嗪）, partial success 1950, chlorpromazine anti-shock; temperature decrease; quiet
上游充通大￥ History of chlorpromazine Shanghai Jiao Tong University associating with treatment of psychotic patients Hamon tried and succeeded in mania Ann Med -Psychol 1952;110:267-273 milestone of psychopharmacology
Shanghai Jiao Tong University • associating with treatment of psychotic patients • Hamon tried and succeeded in mania • Ann Med -Psychol 1952; 110:267-273 • milestone of psychopharmacology History of chlorpromazine
chlorpromazine 上充通大￥ Shanghai Jiao Tong University Pharmacological properties and clinical uses blockade of DA,a,M,H1,5-HT receptors 1,CNS (1)antipsychotic action (抗精神病作 用) used mainly for schizophrenia (精神分裂症)
Shanghai Jiao Tong University Pharmacological properties and clinical uses blockade of DA, α, M, H1 , 5-HT receptors 1, CNS （1）antipsychotic action （抗精神病作 用） used mainly for schizophrenia （精神分裂症） chlorpromazine
上浒充通大学 Shanghai Jiao Tong University mechanism: blockade of D2 receptor in the meso- cortical and meso-limbic pathways: improving positive symptoms
Shanghai Jiao Tong University mechanism: blockade of D2 receptor in the mesocortical and meso-limbic pathways： improving positive symptoms