4. Special disease Degenerative disease: Parkinson Dis Alzheimer Dis Demyelination disease: multiple sclerosis Psychiatric diseases less understanding Congenital anomalies: high incidence
4. Special disease : Degenerative disease: Parkinson Dis. Alzheimer Dis. Demyelination disease: multiple sclerosis Psychiatric diseases less understanding Congenital anomalies: high incidence 7
Disease of cns Basic pathological changes of cells Common complications ■ Infection disease a Hemodynamic Derangement Cerebral Vascular disorders ■umor
Disease of CNS ◼ Basic pathological changes of cells ◼ Common complications ◼ Infection disease ◼ Hemodynamic Derangement & Cerebral Vascular Disorders ◼ Tumor
Part i Basic pathological changes of cells in cns
Part I Basic pathological changes of cells in CNS
Cells in cns dendrite nuc eus Neuron glia cells(astrocyte oligodendrocyte ependyma) axon astrocyte blood vessels microglia Neuropil pI 神经毡 process of the cells in the CNs to form a delicate fibrillary background
Cells in CNS Neuron glia cells (astrocyte oligodendrocyte ependyma) blood vessels microglia Neuropil 神经毡 process of the cells in the CNS to form a delicate fibrillary background
Neuron(神经元) 1. Central Chromatolysis(中央性尼氏小体溶解) Cause: axonal injury, Viral infection, deficiency of vit. B, anoxia. Morphology: NormalNeuron Central Chromatolysis Sequalae: In early stage, increased dissociated ribosome from RER may facilitate protein synthesis. The change would be reversible, if cause abolished. Insistent change may lead to neuronal death
Neuron（神经元） 1.Central Chromatolysis (中央性尼氏小体溶解) Cause： axonal injury, Viral infection, deficiency of Vit.B, anoxia. Morphology: Sequalae: In early stage, increased dissociated ribosome from RER may facilitate protein synthesis. The change would be reversible, if cause abolished. Insistent change may lead to neuronal death. Normal Neuron Central Chromatolysis