Resistance to breathing 米 Elastic of the lung Elastic ~Compliance CL=1/RL=△V/△PL(L/cmH2O) Static compliance (Cs)of the lung S shaped curve,divided into 3 portions Flattened upper portion Steep middle portion Flattened lower portion Special compliance (Csp) Csp=CL/TLC
* Resistance to breathing Elastic ~ of the lung Elastic ~ & Compliance CL=1/RL=VL/PL(L/cmH2O) Static compliance (Cst) of the lung S shaped curve, divided into 3 portions Flattened upper portion Steep middle portion Flattened lower portion Special compliance (Csp) Csp = CL/TLC
0.5 肺容积 呼气 0.25 吸气 Static compliance (Cst)of the lung
Static compliance (Cst) of the lung
100 40 RV -20 S shaped compliance curve of the lung
S shaped compliance curve of the lung
Source of elastic of the lung Elastic tissue (1/3)&Alveolar surface tension (2/3) Pulmonary surfactant Nature:A lipoprotein,Main lip component is DPL Characteristics:Both hydro-philia &-phobicity Source:Type I alveolar epithelial cells Distribution:Inner surface of the alveoli Action:Reduce the alveolar surface tension Significance:Decrease the inspiratory resistance, Stabilize the volume pressure in the alveoli, Prevent pulmonary edema
Source of elastic ~ of the lung Elastic tissue (1/3) & Alveolar surface tension (2/3) Pulmonary surfactant Nature: A lipoprotein, Main lip component is DPL Characteristics: Both hydro-philia & -phobicity Source: Type II alveolar epithelial cells Distribution: Inner surface of the alveoli Action: Reduce the alveolar surface tension Significance: Decrease the inspiratory resistance, Stabilize the volume & pressure in the alveoli, Prevent pulmonary edema