一雜0 C门C Section 2 commonly-used antiepileptic drugs 11
11 Section 2 commonly-used antiepileptic drugs
Common/y-used antiepileptic drugs 1. phenytoin sodium(苯妥英钠 2 barbiturates: phenobarbital(苯巴比妥) primidone(扑米酮) 3. ethosuximide(乙琥胺) 4. benzodiazepines: diazepam(地西泮 nitrazepam(硝西泮) clonazepam(氯硝西泮) 5 sodium valproate丙戊酸钠) 6. carbamazepine(卡马西平 7. newer drugs: lamotrigine(拉莫三嗪) topiramate(托吡酯)妥泰
12 1. phenytoin sodium (苯妥英钠) 2. barbiturates: phenbarbital (苯巴比妥) primidone (扑米酮) 3. ethosuximide(乙琥胺) 4. benzodiazepines: diazepam (地西泮) nitrozepam (硝西泮) clonazepam (氯硝西泮) 5. sodium valproate (丙戊酸钠) 6. carbamazepine (卡马西平) 7. newer drugs: lamotrigine (拉莫三嗪) topiramate ( 托吡酯) 妥泰 Commonly-used antiepileptic drugs
1. Phenytoin Sodium (苯妥英钠, Dilantin,大仑丁) 苯妥英钠片 M品nls
13 1. Phenytoin Sodium （苯妥英钠, Dilantin, 大仑丁）
(Pharmacological actions) Can not inhibit the discharge of neuron > Prevent the diffusion in normal neuron by inhibiting post tetanic potentiation(PTP PTP:反复高频电刺激(强直刺激)突触前神经纤维, 引起突触传递易化,使突触后纤维反应增强的 现象,在癫痫发作中具有重要作用
14 【Pharmacological actions】 ØCan not inhibit the discharge of neuron ØPrevent the diffusion in normal neuron by inhibiting post tetanic potentiation (PTP) PTP: 反复高频电刺激(强直刺激)突触前神经纤维， 引起突触传递易化，使突触后纤维反应增强的 现象，在癫痫发作中具有重要作用