dOnce performed, risk assessments should be reviewed routinely and revised when necessary, taking into consideration he acquisition of new data having a bearing on the degree of risk and other relevant new information firom the scientific literature
❑Once performed, risk assessments should be reviewed routinely and revised when necessary, taking into consideration the acquisition of new data having a bearing on the degree of risk and other relevant new information from the scientific literature
One of the most helpful tools available for performing a microbiological risk assessment is the listing of risk groups for microbiological agents However, simple reference to the risk grouping for a particular agent is insufficient in the conduct of a risk assessment. There are other factors that should be considered:
One of the most helpful tools available for performing a microbiological risk assessment is the listing of risk groups for microbiological agents . However, simple reference to the risk grouping for a particular agent is insufficient in the conduct of a risk assessment. There are other factors that should be considered:
1. Pathogenicity of the agent and infectious dose 2. Potential outcome of exposure 3. Natural route of infection 4. Other routes of infection, resulting from laboratory manipulations( parentera肠道的, airborne, ingestion) 5. Stability of the agent in the environment 6. Concentration of the agent and volume of concentrated material to be manipulated
1. Pathogenicity of the agent and infectious dose 2. Potential outcome of exposure 3. Natural route of infection 4. Other routes of infection, resulting from laboratory manipulations (parenteral非肠道的, airborne, ingestion) 5. Stability of the agent in the environment 6. Concentration of the agent and volume of concentrated material to be manipulated
7. Presence of a suitable host(human or animal) 8. Information available from animal studies and reports of la boratory-acquired infections or clinical reports 9. Laboratory activity planned( sonication声波降解, aerosolization, centrifugation, etc. 10. Any genetic manipulation of the organism that may extend the host range of the agent or alter the agents sensitivity to known, effective treatment regimens 11. Local availability of effective prophylaxis fior therapeutic interventions
7. Presence of a suitable host (human or animal) 8. Information available from animal studies and reports of laboratory-acquired infections or clinical reports 9. Laboratory activity planned (sonication声波降解, aerosolization, centrifugation, etc.) 10. Any genetic manipulation of the organism that may extend the host range of the agent or alter the agent’s sensitivity to known, effective treatment regimens 11. Local availability of effective prophylaxis预防or therapeutic interventions