UNIV Sexually 7andmatted Dieade, STD In the past decade, the spectrum of sexually transmitted disease (STD) has widened considerably important Sexually-trasmitted diseases (veneral diseases) Micro-organisms Diseases H AIDs HS(Herpes Simplex virus) Genital Herpes, Neonatal herpes HPV(human papillomavirus) Condyloma acuminatum, Cervical displasia HBV(Hepatitis B virus) Hepatitis Chlamydia trachomatis(L1-L3) Lymphogrannuloma venereum Chlamydia trachomatis( D-K Urethritis, Cervicitis, (Non-Gonorrhoeae) Mycoplasmas Ureaplasmas Urethritis Neisseria gonococcus Gonorrhoea Treponema pallidum Syphilis Haemophilus ducreyi Chancroid Calymmatobacterium Granuloma inguinale
Sexually Transmitted Disease, STD In the past decade, the spectrum of sexually transmitted disease (STD) has widened considerably
UNIV ◆ An important STD Multiple clinical presentations(thus designated the great imposter)2) ◆ chronic and slowly progressiⅳe involve many vital organs in late period
Syphilis (Lues) An important STD Multiple clinical presentations (thus designatied the great imposter) chronic and slowly progressive involve many vital organs in late period
UNIV Etiology Pathogen: Spirochete Treponema pallidum can not be cultured detectable by silver stains darkfield examination
Etiology Pathogen: Spirochete Treponema pallidum can not be cultured detectable by silver stains, darkfield examination
UNIV Tiandmiodion ◆Mode sexual intercourse(95%) ◆ Acquired sypilis transplacental transmission ◆ Congenital sypilis
Transmission Mode: sexual intercourse (>95%) Acquired sypilis transplacental transmission Congenital sypilis
UNIV Traverse abraded skin and mucosa Enter lymph Latent period circulation 10-90 days average at 21 days Travel through blood and reach various organs and tissue
Pathogenesis Traverse abraded skin and mucosa Enter lymph circulation Travel through blood and reach various organs and tissue Latent period: 10-90 days, average at 21 days