Two h-symmetry-breaking Cso isomersstabilizedby chlorination#1809C60#1,804CcoClg(1)0Cl12 (2)060YUAN-ZHITAN*ZHAO-JIANGLIAO*ZHUO-ZHENQIAN,RUI-TINGCHEN,XINWU,HUALIANG,XIAOHANFENGZHU,SHENG-JUNZHOU,ZHIPINGZHENG,XINLU,SU-YUANXIEt,RONG-BINHUANGANDLAN-SUNZHENGNatureMaterials,2008,7,790
Nature Materials, 2008, 7, 790
Chlorofullerenesfeaturing triplesequentiallyfusedpentagonsXie S.Y., Lu X., Zheng, L.Set alNature Chem. 2010,2, 269#540Cs4Clg (a),#864C56Cl12 (b),#4,169C66Cle (c),#4,169C66Ci10 (d)
Chlorofullerenes featuring triple sequentially fused pentagons Xie S.Y., Lu X., Zheng, L.S. et al Nature Chem. 2010, 2, 269. #540C54Cl8 (a), #864C56Cl12 (b), #4,169C66Cl6 (c), #4,169C66Cl10 (d)
EndohedralMetallofullerene:Sc4@C82 (C3v) vs. Sc,C2@C80 (lh)QM-predictedin2006X-ray diffract.in 2009Proposed.C.o.ScSc@C82AE = 0.0 kcal/mol△E=28.8kcal/molC,-@(Sc3+)4@C80*--Ih(Sc2+)4@Cs28ARussian-Doll endofullereneX.Lu,J.Phys.Chem.B.2006,110,11098:Shinohara, H. Rep. Prog. PhysLu & Wang,J.Am.ChemSoc.2009,131,166462000, 63,843HighlightedbyC&ENandNat.Chem
Endohedral Metallofullerene: Sc4@C82 (C3v) vs. Sc4C2@C80 (Ih ) • (Sc2+) 4@C82 8- Shinohara, H. Rep. Prog. Phys. 2000, 63, 843. Proposed QM-predicted in 2006 X-ray diffract. in 2009 Sc4@C82 DE = 28.8 kcal/mol DE = 0.0 kcal/mol C2 6-@(Sc3+)4@C80 6- -Ih A Russian-Doll endofullerene X.Lu, J. Phys. Chem. B. 2006, 110, 11098; Lu & Wang, J. Am. Chem. Soc. 2009, 131, 16646. Highlighted by C&EN and Nat. Chem
Role of Structural Chemistryin Life Science
Role of Structural Chemistry in Life Science
What do proteins do ?Proteins are the basis of how biology gets thingsdone.As enzymes, they are the driving force behindall of the biochemical reactions which makesbiologyworkAs structural elements,theyarethemainconstituentsofourbones,muscles,hair,skinandbloodvesselsAs antibodies, they recognize invadingelementsand allowtheimmune system togetrid ofthe unwanted invaders
What do proteins do ? Proteins are the basis of how biology gets things done. • As enzymes, they are the driving force behind all of the biochemical reactions which makes biology work. • As structural elements, they are the main constituents of our bones, muscles, hair, skin and blood vessels. • As antibodies, they recognize invading elements and allow the immune system to get rid of the unwanted invaders