Chapter5 Stereochemistry(立体 化学): Chiral molecules(手性分 5.isomerism Constitutional isomers and stereoisomers (构形异构与立体异构)
Chapter 5 Stereochemistry（立体 化学）: Chiral Molecules（手性分 子） 5.1 Isomerism: Constitutional isomers and Stereoisomers (构形异构与立体异构）
Subdivison of isomers (Different compounds with same molecular formula) Constitutional isomers Stereoisomers (somers that have the same connectivity but that 1. CH3CH2CH-CH3( CH3)2CHCH3 differ in the arrangement of their atoms in space 2. CH3CHyCH2CI(CH3)2CHCI 3. CH3CH2OH CH3OCH Enantiomers(对映异构) Diastereomers(非立体 ( Stereoisomers that are mirror images of each other, 对映异构) but it is notsuperposa互为实物与镜象关系, (Stereoisomers that are not 但不重叠) mirror images of each ther)
Subdivison of isomers (Different compounds with same molecular formula) Constitutional isomers Stereoisomers (Isomers that have the same connectivity but that differ in the arrangement of their atoms in space 1. CH3CH2CH2CH3 (CH3 ) 2CHCH3 2. CH3CH2CH2Cl (CH3 ) 2CHCl 3. CH3CH2OH CH3OCH3 Enantiomers (对 映 异 构 ） Diastereomers (非 立 体 对 映 异 构 ) (Stereoisomers that are mirror images of each other, but it is notsuperposable 互 为 实 物 与 镜 象 关 系 ， 但 不 重 叠 ) (Stereoisomers that are not mirror images of each other)
Stereoisomers Isomers that have the same connectivity but that differ in the arrangement of their atoms in space Enantiomers(对映异构) Diastereomers(非立体对映异构 (Stereoisomers that are mirror images of each other, but it is notsuperposable互为实物与镜象关系,S Stereoisomers that are not mirror 但不重叠) images of each other) CH3 CH HILlII cH3cH∞x HO H3CH2C OH CH2CH3 H H CH H 2-butanol Cis trans
Stereoisomers (Isomers that have the same connectivity but that differ in the arrangement of their atoms in space Enantiomers (对 映 异 构 ） Diastereomers (非 立 体 对 映 异 构 ) (Stereoisomers that are mirror images of each other, but it is notsuperposable 互 为 实 物 与 镜 象 关 系 ， 但 不 重 叠 ) (Stereoisomers that are not mirror images of each other) CH3 H3CH2C OH H CH3 HO CH2CH3 H 2-butanol CH3 H CH3 H CH3 H H CH3 Cis - trans - H Cl H Cl H Cl Cl H
5.2 Enantiomers and chiral molecules a Chiral molecule is defined as one that is not superposable on its mirror image The chiral molecule and its mirror image are enantiomers, and the relationship between the chiral molecule and its mirror image is defined as enantiomeric(对映异构) The word chiral comes from the greek word Cheir, meaning hand. That means relationship between left hand and right hand
5.2 Enantiomers and chiral molecules • A Chiral molecule is defined as one that is not superposable on its mirror image. • The chiral molecule and its mirror image are enantiomers, and the relationship between the chiral molecule and its mirror image is defined as enantiomeric (对映异构）. • The word chiral comes from the Greek word Cheir, meaning ‘hand’. That means, relationship between left hand and right hand
52 Chiral molecules(手性分子) l( Chira)手性——物质分子与其镜象相似而不 重合的特征。 左手镜右手 Left hand〔左手)和 right hand(右手)相似而不重合
5.2 Chiral molecules (手性分子) • 1.(Chiral)手性——物质分子与其镜象相似而不 重合的特征。 Left hand (左手)和right hand(右手) 相似而不重合