Table 12-1: The subunits of RNA polymerases Prokaryotic Eukaryotic Bacterial Archaeal RNAP I RNAP II RNAPⅢ Core Core (Pol I) (Pol I) (Pol li) A'/A" RPA1 RPB1 RPC1 β RPA2 RPB2 RPC2 RPC5 RPB3 RPC5 RPC9 RPB11 RPC9 K RPB6 RPB6 RPB6 [+6 others] [+9 others] [+7 others] [+11 others
12 Table 12-1: The subunits of RNA polymerases
The bacterial RNa polymerase The core enzyme alone synthesizes rna 13
13 The bacterial RNA polymerase The core enzyme alone synthesizes RNA a a b b’ w
prokaryotic β'Fig12-2RNAP Comparison c The same color indicate the homologous of the two enzymes eukaryotic RPB2 RPB3 RPB1 RPB11 RPB6 14
14 a a b’ w RPB3 RPB11 RPB2 RPB1 RPB6 Fig 12-2 RNAP Comparison The same color indicate the homologous of the two enzymes prokaryotic eukaryotic b
Crab claw" shape of RNAP (The shape of DNA pol is Active center cleft 15
15 “Crab claw” shape of RNAP (The shape of DNA pol is__) Active center cleft
There are various channels allowing DNA RNA and ribonucleotides (rntPs) into and out of the enzyme s active center cleft 16
16 There are various channels allowing DNA, RNA and ribonucleotides (rNTPs) into and out of the enzyme’s active center cleft