Bloodcellsbloodsmearstains withWrightorGiemsa080
blood smear blood smear stains with Wright or Giemsa stains with Wright or Giemsa Blood cells
Erythrocytes>biconcavedisc,7.5μmno nuclei, no organelles>hemoglobin:（Hb）transporting&binding O, and CO2 carbon monoxideflaxible>bloodgroup(ABO)agglutinogen>lifespan:120dGroupAGroupBGroupABGraupoRad bloo>normalconcentrationcelltypefemale:3.9-5.5X106/uL祥恭茶Artibodlkmale:4.1-6X10%/μLpresemtAnd-BAn-ANeneAnd-andAnAntigenaAaridEAantigenBantigenpresentNoneartleens
biconcave disc, 7.5μm no nuclei，no organelles hemoglobin: （Hb）transporting & binding O2 and CO2 carbon monoxide flaxible blood group (ABO) agglutinogen life span: 120 d normal concentration female: 3.9-5.5×106/μL male: 4.1-6×106/μL Erythrocytes
MedicalApplication>Anemia: R.B.C<3X1012/L or Hb<100g/Lirondeficiencyismajoereason>Erythrocytosis:anisocytosis>macrocytes>9μm; microcytes<6 μ m;Sicklecelldisease:caused by a mutation of onenucleotide. the triplet GAA for glutamic acid is changedto GUA for valine> hereditary spherocytosis: defects inspectrin molecule;easytobedestructed by macrophages
Medical Application Anemia ：R.B.C < 3 ×1012/L or Hb< 100g/L iron deficiency is majoe reason Erythrocytosis: macrocytes > 9 μm; microcytes < 6 μm; anisocytosis Sickle cell disease: caused by a mutation of one nucleotide. the triplet GAA for glutamic acid is changed to GUA for valine hereditary spherocytosis: defects in spectrin molecule; easy to be destructed by macrophages
ReticulocytesimmatureRBC,justreleasedfrombonemarrow1% of the total number of erythrocytes3-6%in newbornresidual ribosome--- netlike structure(brilliant cresyl blue)Increase in anemia indicator ofhematopoietic capacityofthebonemarrow
Reticulocytes immature RBC, just released from bone marrow 1% of the total number of erythrocytes, 3-6% in newborn residual ribosome- netlike structure (brilliant cresyl blue) Increase in anemia indicator of hematopoietic capacity of the bone marrow
LeukocytesSpherical,nucleate&colorless,6000---10.000/uLClassification:based on specific granules andnonspecificlazurophilic granulesneutrophil: 60 ~ 70%eosinophil: 2 ~ 4%Granulocyte65-70%basophil: 0.5%lymphocyte:28%Agranulocytemonocyte: 5%30-35%
Spherical, nucleate & colorless, 6000-10,000/μL Classification: based on specific granules and nonspecific/azurophilic granules Granulocyte Agranulocyte neutrophil：60～70% eosinophil：2～4% basophil：0.5% lymphocyte：28% 30-35% monocyte：5% 65-70% Leukocytes