清华大学：《生物化学》课程PPT教学课件（英文版）Chapter 7 Proteins Function

eme group Myoglobin β subunit of hemoglobin

Mb Hbo HbB Mb Hbo HbB Mb Hbe HbB NAI--IV IV V AENK PDAvMNP d n t tv DKNy EEKs LEPlsEAIL KLLsHcLl between Hba and G19-R voHA HPGDFGAD AAHLPAB HbB:<50% 120K AI.KKK sDLAHLDNLKGrF PAvHAsL Number of 0Ag identity aas MNKALgLP a m 0] g M b Hba and FLsP HEAELK 140K LAsvsTvL HbβB:27 H 和mp AAK gLHCDKLHVDP K IIR 146H--HCa Hby only ELor DLsH

Identity between Hba and Hbb: < 50% Number of identity AAs among Mb, Hba and Hbb: 27

a2 阝1 1

Asp FGl B subunit a subunit Lys c5 His hc3 (a)

Asp His NH3 COO FG1 HC3 Arg-、Asp Lys COO NH3 HC3 H9 C5 Ns 2 A NH3 COO C5 H9 HC3 His+ A COO NH3 HC3 FG1