The Immune Systen(工) Immunity Innate Adaptative Granulocytes Macrophages Lymphocytes a Innate immune system B-cells T-cells immediately available for combat Adaptive immune system antibody(ab production specific to a determined infectious agent BIC 2005-Introduction to artificial Immune Systems- Dr Leandro Nunes de Castro
BIC 2005 - Introduction to Artificial Immune Systems - Dr. Leandro Nunes de Castro 6 ◼ Innate immune system: ◼ immediately available for combat ◼ Adaptive immune system: ◼ antibody (Ab) production specific to a determined infectious agent The Immune System (II) Granulocytes Macrophages Innate B-cells T-cells Lymphocytes Adaptative Immunity
The Immune System(IIf) Anatomy Primary lymphoid Secondary lymphoid organs organs Tonsils and adenoids Thymus Spleen Peyer's patches Appendi Bone marrow Lymph nodes Lymphatic vessels BIC 2005- Introduction to Artificial Immune SysteHnIs-Df Leandrb Nunes de castro
BIC 2005 - Introduction to Artificial Immune Systems - Dr. Leandro Nunes de Castro 7 ◼ Anatomy The Immune System (III) Lymphatic vessels Lymph nodes Thymus Spleen Tonsils and adenoids Bone marrow Appendix Peyer’s patches Primary lymphoid organs Secondary lymphoid organs
The Immune System (Iv All living beings present a type of defense mechanism Innate Immune System first line of defense controls bacterial infections regulates adaptive immunity composed mainly of phagocytes and the complement system PAMPs and prrs BIC 2005-Introduction to artificial Immune Systems- Dr Leandro Nunes de Castro 8
BIC 2005 - Introduction to Artificial Immune Systems - Dr. Leandro Nunes de Castro 8 ◼ All living beings present a type of defense mechanism ◼ Innate Immune System ◼ first line of defense ◼ controls bacterial infections ◼ regulates adaptive immunity ◼ composed mainly of phagocytes and the complement system ◼ PAMPs and PRRs The Immune System (IV)
The Immune System (v) Adaptive immune system vertebrates have an adaptive immune system that confers resistance against future infections by the same or similar antigens lymphocytes carry antigen receptors on their surfaces. These receptors are specific to a given antigen is capable of fine-tuning the cell receptors of the selected cells to the selective antigens is regulated and down regulated by the innate immunity BIC 2005-Introduction to artificial Immune Systems- Dr Leandro Nunes de Castro
BIC 2005 - Introduction to Artificial Immune Systems - Dr. Leandro Nunes de Castro 9 ◼ Adaptive Immune System ◼ vertebrates have an adaptive immune system that confers resistance against future infections by the same or similar antigens ◼ lymphocytes carry antigen receptors on their surfaces. ◼ These receptors are specific to a given antigen ◼ is capable of fine-tuning the cell receptors of the selected cells to the selective antigens ◼ is regulated and down regulated by the innate immunity The Immune System (V)
The Immune System (VI) Pattern Recognition B-cell bcR or antibody B-cell Receptors(Ab) Epitopes Anti B-cel BIC 2005-Introduction to artificial Immune Systems- Dr Leandro Nunes de Castro 10
BIC 2005 - Introduction to Artificial Immune Systems - Dr. Leandro Nunes de Castro 10 ◼ Pattern Recognition: B-cell The Immune System (VI) B-cell BCR or Antibody Epitopes B-cell Receptors (Ab) Antigen