3. ClassificationHDHodgkin's lymphoma(non-Hodgkin's Iymphoma(NHL
3. Classification Hodgkin’s lymphoma( HD ) non-Hodgkin’s lymphoma(NHL)
二. Hodgkin's lymphoma(Hodgkin's disease, HD)()Introduction1. Age:two peaks of incidenceadult: 15-27 years of ageyoungabout 50 years of age
(Hodgkin’s disease, HD) (一) Introduction 1. Age:two peaks of incidence young adult: 15-27 years of age about 50 years of age 二. Hodgkin’s lymphoma
2.Features① 90% derived from lymph nodeDistinctive neoplastic giant cellReed-sternberg cells(R-S cell)Admixed with:variableinflammatory infiltrationvariable fibrosisBone marrow involved in 10% casesNot transform into leukemia
① 90% derived from lymph node ② Distinctive neoplastic giant cell Reed-sternberg cells(R-S cell) ③ Admixed with: variable inflammatory infiltration variable fibrosis ④ Bone marrow involved in 10% cases Not transform into leukemia 2. Features
(二)Pathological changes1. Gross(1) Sites:cervical LNCommonsupraclavicular LNLate : spleen , liver, bone marrow(2)Enlargement of lymph node
(二)Pathological changes 1. Gross (1) Sites: Common cervical LN supraclavicular LN Late : spleen , liver, bone marrow (2) Enlargement of lymph node
