Medical genetics Chromosome disorders Lecturer: David Saffen Ph D Laboratory for Molecular Neuropsychiatric Genetics Department of Cellular and Genetic Medicine School of Medicine, Fudan University saffen@fudan.edu.cn
Medical Genetics: Chromosome disorders Lecturer: David Saffen. Ph.D. Laboratory for Molecular Neuropsychiatric Genetics Department of Cellular and Genetic Medicine School of Medicine, Fudan University saffen@fudan.edu.cn
Next three lectures Chromosome disorders(Nov. 22) 2. Single gene( Mendelian")disorders(Nov 29) 3. Polygene(complex) disorders(Dec 6 医学遗传学 Textbook of Medical Genetics:医学遗传学 ( Thompson& Thompson医学遗传学)第7版中英改编版 北京大学医学出版社lsBN:978-781116785-6( chapters5-8)
Next three lectures: 1. Chromosome disorders (Nov. 22) 2. Single gene (“Mendelian”) disorders (Nov. 29) 3. Polygene (“complex”) disorders (Dec. 6) Textbook of Medical Genetics: 医学遗传学 (Thompson & Thompson医学遗传学) 第7版中英改编版 北京大学医学出版社ISBN:978-7-81116-785-6 (Chapters 5-8)
Chromosome disorders After listening to this lecture you should have a better understanding of 1. The role karyotype analysis in the discovery and diagnosis of human chromosome disorders 2. The molecular and cellular origins of chromosome abnormalities 3. Several famous chromosome disorders 4. The role of dNa methylation in the regulation of gene expression and human disease
Chromosome disorders After listening to this lecture you should have a better understanding of: 1. The role “karyotype” analysis in the discovery and diagnosis of human chromosome disorders 2. The molecular and cellular origins of chromosome abnormalities 3. Several famous chromosome disorders 4. The role of DNA methylation in the regulation of gene expression and human disease
Outline A. The human genome and its chromosomes B The origin of chromosome abnormalities C Chromosome disorders
Outline: A.The human genome and its chromosomes B. The origin of chromosome abnormalities C. Chromosome disorders
A. The human genome and its chromosomes The human genome Structures of human chromosomes The human karyotype Staining metaphase chromosomes
A. The human genome and its chromosomes • The human genome • Structures of human chromosomes • The human karyotype • Staining metaphase chromosomes