SIRNA
siRNA
sRNA与 MiRNA的区别 1)来源不同: miRNAs derive from genomic loci distinct from other recognized genes, whereas siRNAs often derive from mRNAS, transposons, viruses or heterochromatic dna 2)结构不同: miRNAs are processed from transcripts that can form local rNA hairpin structures, whereas siRNAs are processed from long bimolecular RNA duplexes or extended hairpins 3)加工不同: A single miRNA:mRNA* duplex is generated from each miRNA hairpin precursor molecule, whereas a multitude of sirNa duplexes are generated from each siRNA precursor molecule, leading to many different siRNAs accumulating from both strands of this extended dsRNA 4)保守性不同: miRNa sequences are nearly always conserved in related organisms, whereas endogenous siRNa sequences are rarely conserved These types of differences are the basis of practical guidelines for distinguishing and annotating newly discovered miRNAs and endogenous siRNAs
siRNA与miRNA的区别 1）来源不同：miRNAs derive from genomic loci distinct from other recognized genes, whereas siRNAs often derive from mRNAs, transposons, viruses, or heterochromatic DNA 2）结构不同：miRNAs are processed from transcripts that can form local RNA hairpin structures, whereas siRNAs are processed from long bimolecular RNA duplexes or extended hairpins. 3）加工不同：A single miRNA:miRNA* duplex is generated from each miRNA hairpin precursor molecule, whereas a multitude of siRNA duplexes are generated from each siRNA precursor molecule, leading to many different siRNAs accumulating from both strands of this extended dsRNA. 4）保守性不同：miRNA sequences are nearly always conserved in related organisms, whereas endogenous siRNA sequences are rarely conserved. These types of differences are the basis of practical guidelines for distinguishing and annotating newly discovered miRNAs and endogenous siRNAs
SIRNA的种类 D) natural cis-acting RNA--na-ciRNA natural cis- antisense rnac(压力诱导 SiRNA); 3)repeat-associated short interfering RNAs (rasi-RNAS); 4 heterochromatin siRNA-hc sirnA; 5 scan rNa (scn RNa)
siRNA的种类 1) natural cis-acting RNA—na-ciRNA; 2) natural cis-antisense RNA(压力诱导siRNA); 3) repeat-associated short interfering RNAs (rasi-RNAs); 4) heterochromatin siRNA—hc siRNA; 5 scan RNA (scn RNA)
natural cis-acting RNA 源于外源入侵的病毒产生的小分子双链RNA: 1)植物外源入侵的病毒产生的小分子双链RNA; 2)无脊椎动物外源入的侵病毒产生的小分子双链 RNA
natural cis-acting RNA 源于外源入侵的病毒产生的小分子双链RNA： 1）植物外源入侵的病毒产生的小分子双链RNA； 2）无脊椎动物外源入的侵病毒产生的小分子双链 RNA
DCL4 病毒RNA 病毒RNA TTTTTTTTTTTTTTTTT 植物病 病毒复制 毒入侵 病毒RNA TTTT haNl viral RNA-dependeted RNA Polymer 诱导产 HEN1 IMro 生的 21nt vral siRNAs 21nt病毒 SIRNA 初生 RNA解旋 RISC SIRNA 病毒RNA 病毒RNA切割
植物病 毒入侵 诱导产 生的 初生 siRNA