Linkage Analysis Neurofibroma,NF RFLP 8 4.7kb▣ 3.0kb
Linkage Analysis Neurofibroma, NF1 RFLP Ⅰ Ⅱ Ⅲ 1 2 1 2 3 4 5 6 7 8 1 2 3 4 5 6 7 8 4.7 kb 3.0 kb
Linkage Analysis 1955,Morton:logarithm of the odds (Lod) +3 is considered evidence for linkage -2 is considered evidence for not linkage
Linkage Analysis 1955, Morton: logarithm of the odds (Lod) ❖ +3 is considered evidence for linkage ❖ -2 is considered evidence for not linkage
Multipoint Linkage Mapping *Three point crosses
Multipoint Linkage Mapping ❖ Three point crosses
Somatic Hybridization Cell fusion:The experimental formation of a single hybrid cell with nuclei and cytoplasm from different somatic cells. *Sendai virus Polyethylene Glycol,PEG Electroporation
Somatic Hybridization Cell fusion: The experimental formation of a single hybrid cell with nuclei and cytoplasm from different somatic cells. ❖ Sendai virus ❖ Polyethylene Glycol, PEG ❖ Electroporation