Types of Acids in the body a volatile acids Can leave solution and enter the atmosphere. H2 CO3(carbonic acid ). Pco2 is most important factor in ph of body tissues
Types of Acids in the Body ◼ Volatile acids: ◼ Can leave solution and enter the atmosphere. ◼ H2CO3 (carbonic acid). ◼ Pco2 is most important factor in pH of body tissues
Types of Acids in the body Fixed acids Acids that do not leave solution Sulfuric and phosphoric acid. Catabolism of amino acids nucleic acids, and phospholipids
Types of Acids in the Body ◼ Fixed Acids: ◼ Acids that do not leave solution. ◼ Sulfuric and phosphoric acid. ◼ Catabolism of amino acids, nucleic acids, and phospholipids
Types of Acids in the body Organic Acids Byproducts of aerobic metabolism, during anaerobic metabolism any during starvation, diabetes. Lactic acid ketones
Types of Acids in the Body ◼ Organic Acids: ◼ Byproducts of aerobic metabolism, during anaerobic metabolism and during starvation, diabetes. ◼ Lactic acid, ketones
Chemical Buffers Act within fraction of a second a Protein HCO3. Phosphate
Chemical Buffers ◼ Act within fraction of a second. ◼ Protein. ◼ HCO3 - . ◼ Phosphate
Proteins coo or NH Largest pool of buffers in the body. pk, close to pH in plasma. Albumin, globulins such as Hb
Proteins ◼ COOH or NH2 . ◼ Largest pool of buffers in the body. ◼ pk. close to pH in plasma. ◼ Albumin, globulins such as Hb