Congenital infections·TORCHS:T- toxoplasma,protozoomO- othersR- rubellaC- cytomegalovirusHherpes, HIVS- syphilis
Congenital infections • T O R C H S : T– toxoplasma, p r o t o z o o m O- others R- rubella C- cytomegalovirus Hherpes, H I V S- syphilis
Clinical Classification of Pathologic Jaundice2.Non-infection Jaundice:IHemolytic disorders---unconjugatedbilirubinemiaA.IsoimmunizationABOincompatibility(85%)bloodgroupOofma-AorBofbb Rhhemolyticdisease (14.6%)bloodgroupRh-(dd)ofma-Rh+(DDorDd)ofbbB..G6PD deficiencyOxidant:antimalarials, some sulphonamides,ciprofloxacinmothballs:spherocytosis
2 . N o n - infection Jaundice: Ⅰ. Hemolytic disorders - unconjugated bilirubinemia A. Isoimmunization ABO incompatibility ( 85%) : blood group O of ma – A or B of bb Rh hemolytic disease ( 14.6%) blood group Rh- (dd) of ma – Rh+ (DD or Dd) of bb B. G6PD deficiency Oxidant: antimalarials, some sulphonamides, ciprofloxacin, mothballs C. spherocytosis Clinical Classification of Pathologic J a u n d i c e