河北医科大学药学院 三十世纪 天然产物化学的伟大成 ~第一部分~ 李力更教授编辑整理 河北医科大学药学院 天然药物化学教研室 In 20th Century The Great Achievements in Chemistry of Natural Products Part I Department of Medicinal Natural Products College of Phar tical Science Hebei Medical University 天然药物化学教研室 1
河北医科大学药学院 天然药物化学教研室 1 1 二十世纪 天然产物化学的伟大成就 ～第一部分～ 河北医科大学药学院 天然药物化学教研室 李力更 教授 编辑整理 2 In 20th Century The Great Achievements in Chemistry of Natural Products Part I Department of Medicinal Natural Products College of Pharmaceutical Science Hebei Medical University
河北医科大学药学院 Who is he His achievements in organic synthesis were: Cholesterol(胆固醇)，Cortisone(可的 松，皮质酮)，Lanosterol（羊毛甾醇)， Strychnine(士的宁)，Lysergie acid(麦角 酸)，Reserpine(利血平)，Chlorophyll(叶 绿素)，Tetracycline（四环素)，Colchicine (秋水仙碱)，Cephalosporin C(头孢子菌素 C)and Vitamin B2(维生素B12). Who is he And his breathtaking catalog in structure determination includes: Penicillin(青霉素)，Strychnine(士的 宁)，Patulin(棒曲霉素)，Terramycin(土 霉素)，Aureomycin(金霉素)，Cevine(沙 巴达碱)，Magnamycin(碳霉素)，Gliotoxin (胶霉毒素)，Oleandomycin(竹桃霉素)， Streptonigrin(链黑菌素)，Tetrodotoxin(河 心豚毒素)· 天然药物化学教研室 2
河北医科大学药学院 天然药物化学教研室 2 3 Who is he ? His achievements in organic synthesis were: Cholesterol（胆固醇），Cortisone（可的 松 , 皮 质 酮 ） ， Lanosterol （ 羊 毛 甾 醇 ） ， Strychnine（士的宁），Lysergic acid（麦角 酸），Reserpine（利血平），Chlorophyll（叶 绿素），Tetracycline（四环素），Colchicine （秋水仙碱），Cephalosporin C（头孢子菌素 C）and Vitamin B12（维生素B12）. 4 And his breathtaking catalog in structure determination includes: Penicillin （ 青 霉 素 ） ， Strychnine （ 士 的 宁）， Patulin （棒曲霉素），Terramycin（土 霉素）， Aureomycin （金霉素），Cevine（沙 巴达碱），Magnamycin（碳霉素），Gliotoxin （胶霉毒素），Oleandomycin（竹桃霉素）， Streptonigrin（链黑菌素），Tetrodotoxin（河 豚毒素）. Who is he ?
河北医科大学药学院 In 20th century The Noble Winner The master of natural products The foremost synthetic organic chemis Robert Burns WOODWARD (April10,1917-Ji8,979) Boston.Massachusetts fath mother had to work hard to support he 天然药物化学教研室 3
河北医科大学药学院 天然药物化学教研室 3 In 20th century The Noble Winner The master of natural products The foremost synthetic organic chemist Robert Burns WOODWARD （April 10, 1917- July 8, 1979） 6 Bob Woodward was born in Boston, Massachusetts. His father died when Bob was less than two years old, and his mother had to work hard to support her son. Boston, Massachusetts
河北医科大学药学院 Quincy,Massachusetts Bob's early education was in the Ouincy,Massachusetts public schools.During this period he was allowed to skip three years,thus enabling him to finish grammar and high schools in nine years. At age 14,Woodward bought a copy of Ludwig Gattermann's Practical Methods of Organic Chemistry Published by the MacMillan Company,1909 Prof Ludwig Gattermann (1860-1920) Heidelberg University,Germany Later in his life,Woodward did nothing to discourage a persistent legend that he had performed all the experiments in Gattermann's book. 天然药物化学教研室 4
河北医科大学药学院 天然药物化学教研室 4 7 Bob`s early education was in the Quincy, Massachusetts, public schools. During this period he was allowed to skip three years, thus enabling him to finish grammar and high schools in nine years. Quincy, Massachusetts 8 At age 14, Woodward bought a copy of Ludwig Gattermann's Practical Methods of Organic Chemistry. Prof. Ludwig Gattermann ( 1860-1920 ) Heidelberg University, Germany Later in his life, Woodward did nothing to discourage a persistent legend that he had performed all the experiments in Gattermann's book. Published by the MacMillan Company, 1909
河北医科大学药学院 Massachusetts Institute of Technology MIT) “Mind and Hand" nd his s were uraged.In just four ime he was only 20 years old of age. 6 Harvard University Let Plato be your friend and Aristotle, but more let your friend be truth. Woodward joined the chemistry departmentat Harvard University. where he worked until his passed away in 1979. 天然药物化学教研室 5
河北医科大学药学院 天然药物化学教研室 5 9 Massachusetts Institute of Technology ( MIT ) In 1933 at the age of 16, Woodward enrolled in the MIT to study chemistry, although he also had interests at that time in literature, mathematics, and architecture. His unusual talents were soon apparent to the MIT faculty, and his needs for individual study and intensive effort were met and encouraged. In just four years Woodward obtained both bachelor's and doctoral degrees. At that time he was only 20 years old of age. “Mind and Hand” 10 Harvard University Woodward joined the chemistry department at Harvard University, where he worked until his passed away in 1979. Let Plato be your friend and Aristotle, but more let your friend be truth