Introducing the molecules FtsZ function: Assembly of a polymeric ring of the tubulin-like GTPase FtsZ (Z ring The z-ring is localized to the center by the actions of the MinC, MinD, and MinE proteins MinC inhibits the initiation of the z ring Minc colocalizes with MinD In wild-type(Wt)cells, MinC/d forms a polar pattern that oscillates between the poles keeping the center free for initiation of cell division Thus, virtually all of MinC/d dynamically assembles on the membrane in the shape of a test tube covering the membrane from one pole up to approximately midcel
Introducing the molecules: - FtsZ function: Assembly of a polymeric ring of the tubulin-like GTPase FtsZ (Z ring). The Z-ring is localized to the center by the actions of the MinC, MinD, and MinE proteins. - MinC inhibits the initiation of the Z ring. MinC colocalizes with MinD. In wild-type (WT) cells, MinC/D forms a polar pattern that oscillates between the poles, keeping the center free for initiation of cell division. Thus, virtually all of MinC/D dynamically assembles on the membrane in the shape of a test tube covering the membrane from one pole up to approximately midcell. 12
Most of MinE accumulates at the rim of this tube in the shape of a ring( the e ring). The rim of the MinC/d tube and associated E ring move from a central position to the cell pole until both the tube and ring vanish. Meanwhile, a new MinC/d tube and associated E ring form in the opposite cell half, and the process repeats, resulting in a pole-to-pole oscillation cycle of the division inhibitor a full cycle takes about 50 s Image removed due to copyright considerations
Most of MinE accumulates at the rim of this tube, in the shape of a ring (the E ring). The rim of the MinC/D tube and associated E ring move from a central position to the cell pole until both the tube and ring vanish. Meanwhile, a new MinC/D tube and associated E ring form in the opposite cell half, and the process repeats, resulting in a pole-to-pole oscillation cycle of the division inhibitor. A full cycle takes about 50 s. Image removed due to copyright considerations. 13