Medical Genetics The Philadelphia Chromosome and Chronic Myelogenous Leukemia(CML) Normal chromosomes Translocated Chromosomes Trans location fused abl gene abl-bcr bcr gene gene→ 9 22 22(Philadelphia elongated chromosome) The translocated abl gene inserts into the bcr gene. The two genes fuse The altered abl gene functions improperly, resulting in CML
Medical Genetics
Medical Genetics d53 dert 8日 9 22 9teg;22)22
Medical Genetics