The wobble rules a The pairings permitted are those give ribose-ribose distances close to that of the standard a:u or gic base pairs. The ribose ribose distances o Purine-purine: too long o Pyrimidine-pyrimidine: too short
The Wobble Rules ◼ The pairings permitted are those give ribose-ribose distances close to that of the standard A:U or G:C base pairs. ◼ The ribose-ribose distances: ⚫ Purine-purine: too long ⚫ Pyrimidine-pyrimidine: too short
anticodon codon anticodon arm of tRNA anticodon U C mRNA chain ribose 5 A GA35 AGG3 ribose codon inosine-cytosine U in the first(5)anticodon position can pair woth A or G ribose ribose cc inosine-uracil 5 GGU13 5 GGC3 5 3 I in the first (5)anticodon position can pair wth U. C. or A The ribose-ribose bose inosine-adenine distances for the wobble codon or anticodon codon or anticodon pairs are close to those of oH—N A:U or G:C base pairs ibase Fiqure 15-2 uarsine-uraci Wobble base pairing
Figure 15-2 Wobble base pairing The ribose-ribose distances for the wobble pairs are close to those of A:U or G:C base pairs