phosphofructokinase CH,O-P 磷酸果糖激酶 CH,OH Mg2 ATP CH,O-P ADP 6-磷酸果糖 1,6二磷酸果糖 fructose-6-phosphate 1,6-fructose-bisphosphate 反应不可逆
6-磷酸果糖 磷酸果糖激酶 ATP ADP Mg2+ 1，6二磷酸果糖 P CH2O-P CH2OH O CH2O-P CH2O- O fructose-6-phosphate 1,6-fructose-bisphosphate phosphofructokinase 反应不可逆
2、1,6-二磷酸果糖 2分子磷酸丙糖 1,6-fructose-bisphosphate triose phosphate CH2O-P ℃=0 磷酸二羟丙酮 aldolase CH2OH dihydroxyacetone 醛缩酶 phosphate CH2O-P triose phosphate isomerase CHO 1,6二磷酸果糖 CH,OH 3-磷酸甘油醛 CH2O-P glyceraldehydes-3-phosphate
2、1，6-二磷酸果糖 2分子磷酸丙糖 1,6-fructose-bisphosphate triose phosphate 1，6二磷酸果糖 CH2O-P C=O CH2OH CHO CH2OH CH2O-P 醛缩酶 磷酸二羟丙酮 3-磷酸甘油醛 P CH2O-P CH2O- O aldolase glyceraldehydes-3-phosphate triose phosphate isomerase dihydroxyacetone phosphate
3、3-磷酸甘油醛 丙酮酸 glyceraldehydes-3-phosphate pyruvate glyceraldehydes-3-phosphate dehydrogenase CHO 3-磷酸甘油醛脱氢酶 COO P CH2OH CH2OH CH2O-P NAD+ NADH+H CH2O-P 3-磷酸甘油醛P 1,3二磷酸甘油酸 bisphosphoglycerate 糖酵解中唯一的一步脱氢
3、3-磷酸甘油醛 丙酮酸 glyceraldehydes–3-phosphate pyruvate CHO CH2OH CH2O-P COO CH2OH CH2O-P ～P 3-磷酸甘油醛脱氢酶 NAD+ NADH + H+ Pi 3-磷酸甘油醛 1,3二磷酸甘油酸 糖酵解中唯一的一步脱氢 bisphosphoglycerate glyceraldehydes-3-phosphate dehydrogenase
COO-P 磷酸甘油酸激酶 COOH CH2OH CH2OH CH,O-P ADP Mg2+ ATP CH2O-P 1,3二磷酸甘油酸 3-磷酸甘油酸 bisphosphoglycerate 3-phosphoglycerate 底物水平磷酸化(substrate level phosphorylation) 生成ATP
COO CH2OH CH2O-P ～P 1,3二磷酸甘油酸 COOH CH2OH CH2O-P 磷酸甘油酸激酶 ADP ATP Mg2+ 3-磷酸甘油酸 底物水平磷酸化(substrate level phosphorylation) 生成ATP bisphosphoglycerate 3-phosphoglycerate
Phosphoglycerate mutase enolase COOH 变位酶 COOH 烯醇化酶 COOH CH2OH CHO-P C-O~P CH,O-P CH,OH H20 3-磷酸甘油酸 2-磷酸甘油酸 磷酸烯醇式丙酮酸 3-phosphoglycerate phosphoenolpyruvate 2-phosphoglycerate
COOH CH2OH CH2O-P COOH CHO-P CH2OH COOH C-O～P CH2 = 变位酶 烯醇化酶 H2O 3-磷酸甘油酸 2-磷酸甘油酸 磷酸烯醇式丙酮酸 3-phosphoglycerate 2-phosphoglycerate Phosphoglycerate mutase enolase phosphoenolpyruvate