TABLE 6-1 Adenine and Related Compounds Base Nucleoside Nucleotide Adenine 2'-deoxyadenosine 2'-deoxyadenosine 5-phosphate Structure NH N N N N --P-OCH2 HOCH2.o O. Adenine OH OH H OH H Molecular 135.1 251.2 331.2 weight Copyright C 2004 Pearson Education, Inc, publishing as Benjamin Cummings
Phosphodiester linkages: repeating, sugar-phosphate backbone of the polynucleotide chain O、cH2 HO c CH2 G(N-H CH2 P T CH2 C N OH CH2 3 Cp. DNA polarity: is defined by the asymmetry of the 5. nucleotides and the way they are joined
DNA polarity: is defined by the asymmetry of the nucleotides and the way they are joined. Phosphodiester linkages: repeating, sugar-phosphate backbone of the polynucleotide chain
adenine Bases in dNA N adenine H purines guanine N9 guanIne H N cytosine NH pyrimidine H cosine H pyrimidines H thymine thymine 004 Pearson Education, Inc, publishing as benjar
Bases in DNA purines pyrimidines adenine guanine cytosine thymine N9 N1
Each bases has its preferred tautomeric form(Related to Ch 9) amino ImIno N keto enol N H一 H N H H-bond donor H-bond acceptor Copyright o 2004 Pearson Education, Inc. publishing as Benjamin Cummings
DNA STRUCTURE ( ) 2 Each bases has its preferred tautomeric form (Related to Ch 9)
The two strands of the double helix are held together by base pairing in an antiparallel a orientation Which is a stereochemical consequence of the way that adenine and o thy mine and guanine and cytosine, pair with S each other. (Related to replication and transcription) base 12A sugar.phasphate A (22nm →A oo◎ 20A(2m H o Cn phosphate C andN ester chain in bases Copynnht o 2004 Pearson Education, Inc. publishing as Benjamin Cummings
The two strands of the double helix are held together by base pairing in an antiparallel orientation, Which is a stereochemical consequence of the way that adenine and thymine,and guanine and cytosine, pair with each other. (Related to replication and transcription) DNA STRUCTURE ( ) 3