Extents of Injuries primary Gn glomerular injuries--only or dominating changes secondary gn glomerular injuries-a part of systematic diseases diffuse impaired glomeruli>50% focal impaired glomeruli <50% global impaired capillary loops of a glomerule >5070 segmental impaired capillary loops of a glomerule <50%o
Extents of Injuries primary GN glomerular injuries—only or dominating changes secondary GN glomerular injuries— a part of systematic diseases diffuse impaired glomeruli>50% focal impaired glomeruli <50% global impaired capillary loops of a glomerule >50% segmental impaired capillary loops of a glomerule <50%
Pathological types of primary gn Minimal change glomerulonephritis Focal segmental lesions Diffuse glomerulonephritis Unclassified glomerulonephritis
Pathological types of primary GN • Minimal change glomerulonephritis • Focal segmental lesions • Diffuse glomerulonephritis • Unclassified glomerulonephritis
1. Minor Lesions of glomeruli No specific lesions LM--mild proliferation of mesangial cells and accumulation of ECMs minimal change disease, MCD mild mesangial proliferative GN recovery stage of endocapillary gn others
1. Minor Lesions of glomeruli No specific lesions LM—mild proliferation of mesangial cells and accumulation of ECMS • minimal change disease，MCD • mild mesangial proliferative GN • recovery stage of endocapillary GN • others
00 0 000 0 0 MCD (left)normal, (right) fusion effacement of foot processes
MCD (left)normal ,(right) fusion & effacement of foot processes
2. Focal and Segmental Lesions 1) focal and segmental proliferative glomerulonephritis 2) focal and segmental glomerulosclerosis
2. Focal and Segmental Lesions 1) focal and segmental proliferative glomerulonephritis 2) focal and segmental glomerulosclerosis