Comparisons of benign and malignant tumors Characteristics Benign Malignant Differentiation/anaplasia Well-differentiated; structure Some lack of differentiation may be typical of tissue of with anaplasia; structure is origIn often atypical Rate of growth Usually progressive and Erratic and may be slow to slow, mitotic figures are rare rapid; mitotic figures may be and normal numerous and abnormal Local invasion Usually expansile and Usually invasive with circumscribed, do not invade poorly-defined maRgins, or infiltrate the surrounding infiltrate the surrounding normal tissues normal tissues Metastasis absent frequently Recurrence Rarel Frequently Outcome Rarely fatal Usually fatal
Based on the potential to invade and metastasize, the tumors are classified into • Benign • Borderline • malignant Comparisons of benign and malignant tumors
General Features of tumors Gross. shape, size, colour, consistency, texture, capsule, border Microscopic: parenchyma: neoplastic cells stroma: connective tissues and blood vessels
General Features of Tumors • Gross: – shape, size, colour, consistency, texture, capsule, border… • Microscopic: – parenchyma: neoplastic cells – stroma: connective tissues and blood vessels
spherical / solid intra-abdominal fibromatosis
spherical / solid intra-abdominal fibromatosis
2008/0l/31 Spherical cystic serous cystadenoma of ovary
Spherical / cystic serous cystadenoma of ovary
2000-6679 solid/tough white collagenous fibroma
solid / tough / white collagenous fibroma