8.1 Biomaterials: Relative Properties 8.2 Bulk(Mechanical) and Surface Properties 8.3 Reactivity: Molecular Interactions 8.4 Bioadhesion (Tissue Bonding): Physical and Chemical Mechanisms 8.5 Factors Affecting Biomaterials

7.1 Paradigms/Strategies 7.2 Cells 7.3 Matrices 7.4 Regulators

6.1 Performance Specifications 6.2 Biocompatibility 6.3 Degradation 6.4 Risk/Benefit Ratio 6.5 Clinical Trial Design

10.1 Corrosion 10.2 Degradation of polymers

1.1 Objectives of Subject 1.2 Related Subjects at MIT 1.3 Terminology 1.4 How Selected Tissues/Organs Function 1.5 Effects of Trauma and Disease on Function 1.6 Restoration of Function with Implants 1.7 Applications of Medial Devices and Examples Demonstrating the Successful and Unsuccessful Performance of Medical Devices/Implants 1.8 Design Considerations for Medical Devices and Non-medical Structures

2.1 Functional Performance of the Device(and Attachment to Tissue) 2.1.1 Mechanical 2.1.1.1Strength and Modulus of Elasticity: Modulus Matching 2.1.1.2 Tribology 2.1.2.3 Kinematics 2.1.2 Chemical 2.1.2.1 Drug Delivery/Controlled Release System

4.1 Performance Specifications 4.2 Biocompatibility 4.3 Degradation 4.4 Risk/Benefit ratio 4.5 Clinical Trial Design

3.1 Regeneration versus Repair 3.2 Matrices for Tissue Regeneration 3.2.1 Chemistry 3.2.1.1 Synthetic Polymers 3.2.1.2 Analogs of Extracellular Matrix: Collagen-GAG Copolymers 3.2.2 Pore Characteristics 3.2.3 Degradation Rate

5.1 Defining the Clinical Problem 5.2 Anatomical Considerations 5.3 Biomechanical Considerations 5.4 Functional Requirements 5.5 Goodness of Fit 5.6 Fixation

More Problems With Culture 1. The culture concept has been used and misused This notion has traveled around the world it can be considered one of Anthropology's great successes b. Culture has also been distorted 1. Assumptions that cultures have clear boundaries