Enteric(Intrinsic)nervous system Submucosal plexus Meissner's plexus) Myenteric pleXus(Auerbach's plexus Myenteric le XUs Submucosal exus Circular Submucosa Longitudinal muscle
Enteric (Intrinsic) nervous system ◼ Submucosal plexus (Meissner’s plexus) ◼ Myenteric plexus (Auerbach’s plexus)
Neurotransmitters secreted by enteric neurons o Ach, NE, ATP, serotonin, dopamine, cholecystokinin(胆囊收缩素), substance p vasoactive intestinal polypeptide(血管活性肠肽), somatostatin(生长抑素),etc
◼ Neurotransmitters secreted by enteric neurons Ach, NE, ATP, serotonin, dopamine, cholecystokinin（胆囊收缩素）, substance P, vasoactive intestinal polypeptide（血管活性肠肽）, somatostatin（生长抑素）, etc
Roles of enteric nervous system LONGITUDINAL muscle SEROSA MYENTERIC plexus CIRCULAR muscle SUBMUCOSAL plexus MUCOSA Activation of MYENTERIC PLEXUs Activation of SUBMUCOSAL PLEXUS increases tonic contraction increases secretory activity increases intensity of rythmic contractions modulates intestinal absorption increases rate of rythmic contractions increases velocity of conduction
◼ Roles of enteric nervous system
Autonomic nervous system Sympathetic nerve O NE o Inhibitory ( Parasympathetic nerve o Mainly ACh o Stimulatory (+)
Autonomic nervous system ◼ Sympathetic nerve NE Inhibitory (-) ◼ Parasympathetic nerve Mainly ACh Stimulatory (+)
To prevertebral Sympathetic Parasympathetic ganglia, spinal (mainly post (preganglionic cord and brain ganglionic tem Myenteric Plexus Submucosal Plexus Sens Neurons