x ★ Hyperthyroidism Endocrinology Department Zhongshan Hlospital, Fuclan University 于明香 大斗 大学附属中山医院
复旦大学附属中山医院 Hyperthyroidism 于明香 Endocrinology Department Zhongshan Hospital, Fudan University
★ Introduction o Definition Function of thyroidism metabolism many systems excitability f o Most common is diffuse toxic goiter(Graves disease, GD),85% 大学附属中出医院
复旦大学附属中山医院 Introduction l Definition：Function of thyroidism metabolism many systems excitability l Most common is diffuse toxic goiter (Graves disease, GD) , 85%
★ x Various causes Graves disease: 85% Autonomous toxic adenomas of the thyroid Plummers disease or toxic multinodular goiter Jodbasedow disease(lodine- induced HT) Functioning thyroid carcinoma TSH hypersecretion by the pituitary Struma ovarii Subacute thyroiditis Hashimoto's thyroiditis o Thyrotoxicosis factitia o Carcinoma accompanying thyrotoxicosis 算大学附属中山医院
复旦大学附属中山医院 Various causes =Graves disease: 85% =Autonomous toxic adenomas of the thyroid: Plummer's disease or toxic multinodular goiter = Jodbasedow disease(Iodine-induced HT) = Functioning thyroid carcinoma =TSH hypersecretion by the pituitary =Struma ovarii =Subacute thyroiditis =Hashimoto's thyroiditis =Thyrotoxicosis factitia =Carcinoma accompanying thyrotoxicosis
x大 ★ Graves disease ●85% Male to female 1: 4-6 o Chief clinical findings Symptoms due to Hypermetabolism goiter Ophthalmopathy 平 x 附属中山医院
复旦大学附属中山医院 =85% =Male to female 1:4-6 =Chief clinical findings Graves disease X Symptoms due to Hypermetabolism X goitor X Ophthalmopathy
★ Etiology and Pathophysiology o Abnormal immune: TRAb ● Heredity Infection: Molecular mimicry Cytokine Superantigen Spirit irritation 大学附属中出医院
复旦大学附属中山医院 = Abnormal immune: TRAb = Heredity = Infection: Molecular mimicry Cytokine Superantigen = Spirit irritation Etiology and Pathophysiology