Anhui Medical University Content ● Establishment of the primordial cardiovascular system Development of the heart Fetal blood circulation and changes in the circulation after birth Congenital defects of the cardiovascular system EMB OLOGY 6
6 Content Establishment of the primordial cardiovascular system Development of the heart Fetal blood circulation and changes in the circulation after birth Congenital defects of the cardiovascular system Anhui Medical University
Anhui Medical University Establishment of the primordial cardiovascular system Period:in the 3rd-7th weeks of embryonic development ●Origin:mesoderm Significance:provide nutrition and oxygen and remove wastes and carbon dioxide
7 Period: in the 3rd-7th weeks of embryonic development Origin: mesoderm Significance: provide nutrition and oxygen and remove wastes and carbon dioxide Establishment of the primordial cardiovascular system Anhui Medical University
Anhui Medical University Establishment of the promordial cardiovasular system 1)Extra-embryonic blood vessels o The 15th day,mesenchymal cells in the wall of yolk sac proliferate to form isolated cell clusters -blood islands body stalk amnion cavity ectoderm endoderm Primordial heart Yolk sac extra embryonic mesoderm Blood islands
8 The 15th day, mesenchymal cells in the wall of yolk sac proliferate to form isolated cell clusters -blood islands 1) Extra-embryonic blood vessels Establishment of the promordial cardiovasular system Blood islands Yolk sac Primordial heart body stalk extra embryonic mesoderm ectoderm endoderm amnion cavity Anhui Medical University
Anhui Medical University Establishment of the promordial cardiovasular system Peripheral cells endothelial cells endothelial tube Central cells primitive blood cells(blood stem cell) Endothelial tube approach and fuse with each other to form an endothelial tube network Mesenchymal cell body stalk ectoderm endoderm Primordial heart endothelial cell Yolk sac extra embryonic mesoderm Blood islands primitive blood cell
9 Peripheral cells endothelial cells endothelial tube Central cells primitive blood cells (blood stem cell) Endothelial tube approach and fuse with each other to form an endothelial tube network Mesenchymal cell endothelial cell primitive blood cell Establishment of the promordial cardiovasular system Anhui Medical University
Anhui Medical University Establishment of the promordial cardiovasular system ● Endothelial tube network appears in chorionic membrane and body stalk,and connect to vitelline circulation. villi amnion cavity amnion Blood vessel Primordial heart Allantois body stalk Yolk sac chorionic membrane Blood islands Blood vessel 10
10 • Endothelial tube network appears in chorionic membrane and body stalk, and connect to vitelline circulation. chorionic membrane body stalk Establishment of the promordial cardiovasular system Blood islands Yolk sac Primordial heart amnion cavity Blood vessel Blood vessel villi Allantois amnion Anhui Medical University