成分输血的优点 纯度、高浓度、容量小、针对性强、 疗效显著:如要提高患者血小板 3×101L需输机采血小板1人份约250m1 左右,如用全血需300m1以上。 安全:限制不必要的成分的输入量,尤 其是限制白细胞和血浆的输入量。 有利于保存血液的各种有效成分:如PC 于22℃水平震荡可保持3-5天,ⅥI因 V因子、ⅠX因子可在-20℃以下保存 1年,上述血液成分在4℃保存的全血中 短时间内即会失效或失活
成分输血的优点 ◼ 高纯度、高浓度、容量小、针对性强、 疗效显著 : 如 要 提 高 患 者 血 小 板 3×1011/L需输机采血小板1人份约250ml 左右，如用全血需3000ml以上。 ◼ 安全：限制不必要的成分的输入量，尤 其是限制白细胞和血浆的输入量。 ◼ 有利于保存血液的各种有效成分:如PC 于22℃水平震荡可保持3-5天，VIII因 子、V因子、IX因子可在-20℃以下保存 1年，上述血液成分在4℃保存的全血中 短时间内即会失效或失活
常用的成分血 Whole blood donation 500mL Packed red blood cells Platelet rich plasma 200 mL 100 mL ADSOL 300mL Shelf life:42 days at1-6°c Platelets Plasma 50 mL 250mL Shelf life: 5 days at Fresh frozen plasma: Frozen within 8 hours of collection FP24: Frozen within 24 hours of Shelf life:1 year at-18°c Cryoprecipitate 15 mL Shelf life:1 year at-18°c 2011- Volume 42 Number 4. LABMEDICINE 23
常用的成分血
降低输血需求— Williams Hematology 2011
降低输血需求——Williams Hematology 2011
Transfusion of blood during cardiac surgery is associated with higher long-term mortality in low-risk patients EuroScoRE 0-4 and RBC Units 100 Units and No 80 07633 70 34534 1-21484 50 010002000300040005000 Days after surgery Figure 3: Kaplan-Meier survival curve of patients subjected to CABG, AVR, MVR. CABG+ AVR and CABG+mVr and EuroS coRE 0-4 divided on the number of perioperative transfused blood units: 7633 had no blood transfu sion. 1484 had 1-2 units, 534 had 3-4 units, 196 had 5-6 units and 170 more than 6 units. Survival rates were 0.758 0.631. 0.669. 0.643 and 0.525 (P<00001) European Journal of Cardio-Thoracic Surgery 42(2012)114-120
Transfusion of blood during cardiac surgery is associated with higher long-term mortality in low-risk patients
Red blood cell transfusion-dependency implies a poor survival lin primary myelofibrosis irrespective of IPSS and DIPSS 00 0.5 Transfusion-independent 0000 Transfusion-dependent Time since diagnosis (years) Figure 1. Overall survival according to RBC transfusion-dependency at the time of diagnosis in 288 patients with PMF. haematologica 2011; 96(1)