Etiology types Portal hypertension should be divided into three types as its blood flow obstructed positions
• Portal hypertension should be divided into three types as its blood flow obstructed positions. Etiology & Types
ypes re-hepatic pI intra-hepatic →pre- sinusoidal Sinusoidal post-sinusolda post-hepatic
Types pre-hepatic intra-hepatic pre-sinusoidal Sinusoidal post-sinusoidal post-hepatic
Pre-hepatic type the portal vein trunk itself obstruction Congenital deformity: obliteration, stenosis 先天性畸形:闭塞、狭窄 > Thrombosis: portal vein thrombosis, splenic vein thrombosis. ect 血栓形成:门静脉、脾静脉 >Infection: Tropical splenomegaly, ect 感染:热带巨脾综合症 Trauma: arterio-venous fistula. ect 创伤:动静脉瘘
• the portal vein trunk itself obstruction. ➢Congenital deformity: obliteration, stenosis 先天性畸形：闭塞、狭窄 ➢Thrombosis: portal vein thrombosis, splenic vein thrombosis, ect 血栓形成：门静脉、脾静脉 ➢Infection: Tropical splenomegaly, ect 感染：热带巨脾综合症 ➢Trauma: arterio-venous fistula, ect 创伤：动静脉瘘 Pre-hepatic type
Intra-hepatic type About 95% patients belong to this type of portal hypertension a classification by pathology pre-sinusoidal obstructions v sinusoidal obstructions post-sinusoidal obstructions
• About 95% patients belong to this type of portal hypertension • A classification by pathology: ✓pre-sinusoidal obstructions ✓sinusoidal obstructions ✓post-sinusoidal obstructions Intra-hepatic type
Pre-sinusoidal obstruction Schistosomial cirrhosis 血吸虫病 Schistosomial eggs deposit in small branches of portal vein, resulting in obstruction of blood flow and increase of portal vein pressure Primary biliary cirrhosis 原发性胆汁性肝硬化 Chronic active hepatitis 慢性活动性肝炎
• Schistosomial cirrhosis. 血吸虫病 – Schistosomial eggs deposit in small branches of portal vein, resulting in obstruction of blood flow and increase of portal vein pressure. • Primary biliary cirrhosis 原发性胆汁性肝硬化 • Chronic active hepatitis 慢性活动性肝炎 Pre-sinusoidal obstruction