Waston-Crick" pairing The strictness of the rules for Waston-Crickpairing derives from the complementarity both of shape and of hydrogen bonding properties between adenine and thymine and between guanine and cytosine. sugar N一H…○ sugar ximal hydrogen bondi H N3 A sugar sugar
The strictness of the rules for “Waston-Crick” pairing derives from the complementarity both of shape and of hydrogen bonding properties between adenine and thymine and between guanine and cytosine. “Waston-Crick” pairing Maximal hydrogen bonding
A: C incompatibility HH A N: N C sugar N sugar Copyright o 2004 Pearson Education, Inc, publishing as Benjamin Cummings
A:C incompatibility
Nucleosides Nucleoside Nucleotides ● 2-deoxyribose """" 5 O—P—OH"HOCH HOH base H phosphoric acid啮a 〓〓〓〓〓〓〓〓〓 HO HH phosphoester bond O—P—OCH H glycosidic bond nucleotide(dAMP) Copyright C 2004 Pearson Education, Inc, publishing as Benjamin Cummings
glycosidic bond phosphoester bond Nucleosides & Nucleoside Nucleotides
TABLE 6-1 Adenine and Related Compounds Base Nucleoside Nucleotide Adenine 2'-deoxyadenosine 2'-deoxyadenosine 5-phosphate Structure NH Asymmetric N N N N 53°—P—0cH2 HOCH2.o O. Adenine OH OH H OH H Molecular 135.1 251.2 331.2 weight Copyright C 2004 Pearson Education, Inc, publishing as Benjamin Cummings
3’ 5’ Asymmetric
A DNA molecule is composed of two antiparallel polynucleotide chains
A DNA molecule is composed of two antiparallel polynucleotide chains