tubular lumen tubular cell ICF K Nat-K+ ATPase K Na+ NE K kidney ADS, guanylin, K]s, urinary flow rate, pH 90% distal delivery of sodium, impermeable anion Regulation of renal Kt excretion
ICF K+ K+ Regulation of renal K+ excretion kidney 90% ADS, guanylin, [K+ ]s, urinary flow rate, pH, distal delivery of sodium, impermeable anion tubular cell Na+ Na+ -K+ ATPase - - - - tubular lumen K+ Na+
Part 2 Hypokalemia Defined as [ k+]s <3.5 mmol/L may or may not be associated with K deficit?
Part 2 Hypokalemia • Defined as [k+]s < 3.5 mmol/L • may or may not be associated with K deficit?