Term Associations Download all assocation informaton in: D gene association format D RDFXML Fiter associations displayed b nce Code Remove a niter 此图显示了该基因产物 的术语关联(term associations)图,图中 Accession, Term Evidence Reference Assigned by 记录名称“Term”是 996s gene products biological GO REF: 0000004 UniProtKB view in trea process ( va UniProtKB/Swss- Go:0030154:ce GO记录的名字, deferentabon 23925 gene products biological “ Ontology”是该基因 GO REF: 0000004 UniProtKB (via UnIProtKB/ Swiss Go: 0007275: multicellular With SP KW:Kw-c21 产物的特性,如要查看 organismal development oroduets biologica 其分子功能,可点击其 viewin tree process GO: 0007399: nervous systen with sp kwkW9524 Prot 中的一条记录 development 20473 g9n9 products biological GO REF:0000004 UniProtxB “ nervous system view in tree process (via UniProtkB/ Swiss GO: 0045449: regulaton of wth SP KW: KM-0805 celular transcription development”。 35436 gene products cellular GO REF: 0000023 UniProtKB Ws5:5L0191 (va UniProtKB/ Swiss Go: 0005634: nucleus 21250 gene products molecular IEA GD REF:0000004 UnIProtKB view in tree fundtion (via UniprotKB/Swiss GO: 0003677: DNA binding 16342 gene product molecular GO REF: 0000002 UniProtKB mew in tree function (via UniProtkB/Swiss- Go: 0030528: transcription InterPro: IPRO 11598 regulator activity 叫[c]pcm如 n action with this pa的m
此图显示了该基因产物 的术语关联（term associations）图，图中 记录名称“Term”是 GO记录的名字， “Ontology”是该基因 产物的特性，如要查看 其分子功能，可点击其 中的一条记录 “nervous system development
nervous system development Term nformation Term inway Estsmal references+ 5)17 one product associatons. er Accession G0:0007399 此图上部先对神经源 ynonyms related: pan-neural process Detinition The process whose specifc outcome is the progression of nervous tssue over time. from ts formation to s mature 性分化因子6的相关 state.(source: GOC dgh comnent None 信息做简单描述,中 comnunity There have been o comments for this term. If you would lke to vew or partcipate n the community annotation, please continue to the GONuT5 page 间术语系谱(term Eack te to lineage)成阶梯状分 Term Lineage wtch to viewing term parents, splines and chidren 布,记录了GO数据 w Fiiter tree vlew a ater Gene Product Counts 库中全部分子功能所 Tree view Fua r cermet 9 Bacilus ane 处的位置和关系。下 D an: al [372469 gene products] actions 方“ External E H GO: 0008150: bological process (274193 gene products t2n:利动 a n Go: 0032502: developmental process [27802 gene produd rachel wow D G0: 0048856: anatomical structure development [20054 gene products Reference”提供了与 a G0: 00-48731: system develooment [15068 gene products H GO: 0007399 t nervous system development [5317 gene products) o B Go: 0007275: muttelluar organs nal developmen: [2392s gene products] 外部相关数据的链接。 a u Go: 0007399: nervous system development (5317 gene products) D n Go: 0032501: muticellular organismal process(32735 gene productsI a u Go: 0007399 t nervous systen development [3317 gene productsI External References HIPS fancat (2 47.0301 w SP_Kw(1) Kw=0524
此图上部先对神经源 性分化因子6的相关 信息做简单描述，中 间术语系谱（term lineage）成阶梯状分 布，记录了GO数据 库中全部分子功能所 处的位置和关系。下 方“External Reference”提供了与 外部相关数据的链接
Go:08150 biological_process 点击上图右上方的可视化视图 ( graphical view)就更清晰地 Go:03250l Go:032502 显示了分子功能记录之间构成 multicellular organismal process developmental process 的复杂网状结构,既有上下隶 属关系,也存在平行关系 Go:0007275 Go:048856 multicellular anatomical structure org animal development levelopment rt of Go:048731 system development Go:007399 development
点击上图右上方的可视化视图 （graphical view）就更清晰地 显示了分子功能记录之间构成 的复杂网状结构，既有上下隶 属关系，也存在平行关系
BLAST Search The sequence search is performed using either BLASTP or BLASTX(from the WU-BLAST package), depending on the type of the input 2.用序列检索GO数据库 BLAST Query 对于未知基因名的序列,可 以用序列直接检索GO数据库 Enter a UniProt accession or upload a text file of quenes or paste in FASTA sequence(s) Uni Prot accession:□ 点击AmGO首页上方的 Text file(maximum file size 500K) [览 BLAST。 FASTA sequence(s) Sequences should be separated with an empty line 界面风格类似于其他数据库 BLAST搜索的网页,在检索 框中铁如氨基酸或核酸序列, 网页能自动识别并相应地做 LAIACIGGGAGIGGA BLASTP或 BLASTX和数据库 IATI521I3CA5SIIAATAAAACAGEGEGGEGCO 中的序列比对。 这里以检索RPIA基因的序列 Maximum number of sequences: 100 Maximum total length of sequence: 3,000,000 residues 为例,如图所示。 提交查询内容 BLAST settings日 Expect threshold 01 v Maximum number of alignments 50 v BLAST flter: on C off 查内音
2. 用序列检索GO数据库 ◼ 对于未知基因名的序列，可 以用序列直接检索GO 数据库。 点 击 AmiGO 首页上方的 “BLAST”。 ◼ 界面风格类似于其他数据库 BLAST搜索的网页，在检索 框中铁如氨基酸或核酸序列， 网页能自动识别并相应地做 BLASTP或BLASTX和数据库 中的序列比对。 ◼ 这里以检索RPIA基因的序列 为例，如图所示