重蹇路科大骨 ngqing Med山cal University
重麦路科大骨 nongging Medical University Cytologic atypia -Cellular pleomorphism -Nuclear plemorphism -Cytoplasmic plemorphism
◼ Cytologic atypia - Cellular pleomorphism - Nuclear plemorphism - Cytoplasmic plemorphism
國市走等利大子 ongqing Med山eal Uaiver Cellular pleomorphism: variation in size and shape, ▣bizarre cells,. tumor giant cells, small and primitive cells
Cellular pleomorphism: ◼ variation in size and shape, ◼ bizarre cells, ◼ tumor giant cells, ◼ small and primitive cells
圈 重麦等科大昂 nongging Medical University
重蹇等科大学 ongqins里Med山eal Univers Nuclear plemorphism: variation in nuclei shape and size nuclear-cytoplastic ratio may approach 1:1(the normal 1:46 。 dark staining nuclei hyperchromatism-containing an abundant DNA) large nucleoli,two nuclei,even multinuclei giant cell. abundant mitoses,atypical abnormal)mitotic figures- non-symmetry,tripolar,quadripolar,multipolar spindles and abortion types pathologic mitoses nuclear membrane became thick the chromatin is often coarsely clumped)
Nuclear plemorphism: • variation in nuclei shape and size • nuclear-cytoplastic ratio may approach 1:1(the normal 1:4~6) • dark staining nuclei ( hyperchromatism- containing an abundant DNA ) • large nucleoli , two nuclei, even multinuclei giant cell. • abundant mitoses, atypical ( abnormal) mitotic figures - non- symmetry, tripolar, quadripolar, multipolar spindles and abortion types pathologic mitoses • nuclear membrane became thick ( the chromatin is often coarsely clumped)