Mucin 2 v Mucin 2 is particularly Gastrointestinal tract prominent in the gut where it is secreted from goblet N SFB cells in the epithelial lining into the lumen of the large Crypt Ⅷi| Intestine This gel provides an S Mucus。 soluble mucous barrier that serves to protect the Bacteriodetes Lamina Peyers Firmicutes intestinal epithelium pria patch
Mucin 2 is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium 16 Mucin 2
Mucin 4 v This gene encodes an integral membrane glycoprotein found on the cell surface. although secreted isoforms may exist wth EGF-lke doman The major constituents of mucus EGF-lke the viscous secretion that covers MUCA epithelial surfaces such as those ERBB2 Knaso MUCT in the trachea. colon and cervix MUC-4 has been found to play various roles in the progression of cancer, particularly due to its MAPK signaling signaling and anti-adhesive properties which contribute to tumor development and Nudeus( TCFAE metastasis It should be noted that MUC-4 is not found in the gall bladder, Nature Reviews I Cancer pancreas, or liver except in abnormal conditions such as cancer
This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix MUC -4 has been found to play various roles in the progression of cancer, particularly due to its signaling and anti -adhesive properties which contribute to tumor development and metastasis It should be noted that MUC -4 is not found in the gall bladder, pancreas, or liver except in abnormal conditions such as cancer 17 Mucin 4
Vaginal structure(物理屏障) Vagina lumen lactobacilli Antimicrobial peptides Mucus Submucosa YO T cell helial Nonkeratinized stratified squamous epithelium 18
Vaginal structure（物理屏障） 18
Cell-cell structural adhesions occur between epithellal cells Adhesion belt Desmosome Gap junction tight junctions Integrin y业 Selectin adherence junctions v desmosomes Focal adhesion Hemi-desmosome Integ Membrane proteoglycan
19 Cell-cell structural adhesions occur between epithelial cells tight junctions adherence junctions desmosomes