2016.7.8 暑期裸程:共粞徼生物 微生物组的研究方法 谢幼华 病原生物系 54237973 hxie@fudan edu cn
微生物组的研究方法 暑期课程：共栖微生物 2016.7.8 谢幼华 病原生物系 54237973 yhxie@fudan.edu.cn
Human as A Super-organism o Microorganisms are all over the earth Less than 1% of all microorganisms present in diverse natural habitats have been cultured o ahuman is a super-organism comprising the human body and its dwelling microbiota(normal flora Skin, Nose, Oral cavity Throat, Gut(Colon), Vagina, Uretha Super organism
Microorganisms are all over the Earth Less than 1% of all microorganisms present in diverse natural habitats have been cultured A human is a super-organism comprising the human body and its dwelling microbiota (normal flora) Skin, Nose, Oral cavity, Throat, Gut (Colon), Vagina, Uretha Superorganism Human as A Super-organism
Human Gut microbiota Micro biome o the human gut microbiota is a complex ecosystem composed of approximately 1014 bacteria and archaea, as well as fungI and viruses >10 times larger than the human cell complement o The human gut microbiome is the collective genome capacity( genes) of the gut microbiota 150 times larger than the human gene complement with an estimated 3. 3 million microbial genes
Human Gut Microbiota & Microbiome The human gut microbiota is a complex ecosystem composed of approximately 1014 bacteria and archaea, as well as fungi and viruses 10 times larger than the human cell complement The human gut microbiome is the collective genome capacity (genes) of the gut microbiota 150 times larger than the human gene complement, with an estimated 3.3 million microbial genes
The General Composition of the human gut Microbiota o Bacteria constitute the bulk of the gut microbiota o Archaea account for approximately 1% of the microbes in the human intestine o Viral and fungal abundance vary greatly Viral sequences account for between 1x10-5% and 2% of total dna in stool Fungal DNA, typically less than 1%, can be as high as 10%
The General Composition of the Human Gut Microbiota Bacteria constitute the bulk of the gut microbiota Archaea account for approximately 1% of the microbes in the human intestine Viral and fungal abundance vary greatly Viral sequences account for between 1x10–5% and 2% of total DNA in stool Fungal DNA, typically less than 1%, can be as high as 10%
The Main Bacterial Phyla of the Human Gut Microbiota o Seven phyla constitute the bulk of the human gut bacteria Firmicutes 硬壁菌门 Bacteroidetes 拟杆菌门 Proteobacteria 变形菌门 Fusobacteria 梭杆菌门 Verrucomicrobia 疣微菌门 Cyanobacteria 蓝藻细菌门 Actinobacteria 放线菌门 o The firmicutes and bacteroidetes accommodate the most abundant species and constitute over 90% of the human gut microbiota
The Main Bacterial Phyla of the Human Gut Microbiota Seven phyla constitute the bulk of the human gut bacteria Firmicutes 硬壁菌门 Bacteroidetes 拟杆菌门 Proteobacteria 变形菌门 Fusobacteria 梭杆菌门 Verrucomicrobia 疣微菌门 Cyanobacteria 蓝藻细菌门 Actinobacteria 放线菌门 The Firmicutes and Bacteroidetes accommodate the most abundant species and constitute over 90% of the human gut microbiota