Intercellular Desmocollins spac Desmogleins Cell membrane Plakoglobin Cell cytoplasm ○ Plaque proteins D including desmoplakins Keratin intermediate filaments
Non-keratinocytes Melanocyte Langerhans cell Merkel cell
Non-keratinocytes Melanocyte Langerhans cell Merkel cell
Melanocytes Epidermal melanin unit melanocytes are derived from the nerual crest and reside in the basal layer Melanocytes are dendritic cells and contain large number of melanosomes Any one melanocyte is contact with 30-40 keratinocytes through its dendrites form the so-called epidermal melanin unit a Protective barrier against UV
Melanocytes Epidermal melanin unit – melanocytes are derived from the nerual crest and reside in the basal layer – Melanocytes are dendritic cells and contain large number of melanosomes – Any one melanocyte is contact with 30-40 keratinocytes through its dendrites, form the so-called epidermal melanin unit. Protective barrier against UV