Mucosal defenses o Secretion of mucus and bicarbonate into the surface of mucosa o Rapid gastric epithelial regeneration o robust mucosal blood flow to sweep away yarogenions
Mucosal defenses ⚫ Secretion of mucus and bicarbonate into the surface of mucosa ⚫ Rapid gastric epithelial regeneration ⚫ Robust mucosal blood flow to sweep away hydrogenions
morphology o Size: round 2-4cm in diameter o Depth: may penetrate into the muscularis propria o The wall of the ulcer: orderly o The base: clean and plain o The margins: edema of adjacent mucosa and no elevation
morphology ⚫ Size: round,2-4cm in diameter ⚫ Depth: may penetrate into the muscularis propria ⚫ The wall of the ulcer: orderly ⚫ The base: clean and plain ⚫ The margins: edema of adjacent mucosa and no elevation
Microscopic appearance o Open ulcer include four zones from inside to outside) ① necrosis debris ② inflammation granulation ④ scar
Microscopic appearance ⚫ Open ulcer include four zones: ⚫ (from inside to outside） ①necrosis debris ②inflammation ③granulation ④scar