PARAMYXOVIRUSES pleomorphic HN/H/G glycoprotein SPIKES F glycoprotein SPIKES helical nucleocapsid(RNA plus NP protein) lipid bilayer membrane polymerase complex 11 业大学儿童医院传染病教研室
11 M protein helical nucleocapsid (RNA plus NP protein) HN/H/G glycoprotein SPIKES polymerase complex lipid bilayer membrane F glycoprotein SPIKES PARAMYXOVIRUSES pleomorphic
PARAMYXOVIRUS FAMILY properties of attachment protein GENUS GLYCOPROTEINS TYPICAL MEMBERS Paramyxovirus HN,F HPIV1,HPIV3 genus Rubulavirus HPIV2,HPIV4 Genus HN,F mumps virus Morbillivirus H,F measles virus genus Pneumovirus respiratory genus G,F syncytial virus 12 重庆医科大学儿童医院传染病教研室
12 PARAMYXOVIRUS FAMILY properties of attachment protein GENUS GLYCOPROTEINS TYPICAL MEMBERS Paramyxovirus genus HN, F HPIV1, HPIV3 Rubulavirus Genus HN, F HPIV2, HPIV4 mumps virus Morbillivirus genus H, F measles virus Pneumovirus genus G, F respiratory syncytial virus
MUMPS EPIDEMIOLOGY 13 重庆医科大学儿童医院传染病教研室
13 EPIDEMIOLOGY MUMPS
EPIDEMIOLOGY MUMPS Infectious sources Routes of transmission Population susceptibility 14 重庆医科大学儿童医院传染病教研室
14 EPIDEMIOLOGY MUMPS ◼ Infectious sources ◼ Routes of transmission ◼ Population susceptibility
EPIDEMIOLOGY Infectious sources:clinical and subclinical patients Infective stage:Patients are the most infectious from 1-2 days before the onset of swelling till the completely detumescence of the salivary gland 15 重庆医科大学儿童医院传染病教研室
15 EPIDEMIOLOGY ◼ Infectious sources: clinical and subclinical patients ◼ Infective stage: Patients are the most infectious from 1-2 days before the onset of swelling till the completely detumescence of the salivary gland