ET OLOGY 6 重庆医科大学儿童医院传染病教研室
6 ETIOLOGY
Genus Paramyxovirus Human Parainfluenza Virus (1-4) Genus Rubulavirus Mumps Subfamily Genus Morbillivirus Paramyxovirinae 。Measles amily Genus Henipavirus Nipah virus and Hendra Virus aram o These viruses are animal paramyxoviruses capable of jumping species,and causing severe,often fatal disease in humans.This makes them a concerning emerging infection. o The natural reservoir of both is thought to be bats of the genus Pteropus.Humans become infected though close association with infected domestic animals.Neither is spread person-to-person o Hendra viruses cause respiratory illness with severe flu-like symptoms.Nipah virus causes encephalitis in Southeast Asia and in Australia. Genus Pneumovirus Subfamily ·RsV Pneumovirinae Genus Metapneumovirus Metapneumovirus 更大医科人字儿单医觉专华丙致至
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ETIOLOGY-MUMIPORGRUSUS RV MaV Phylogenetic tree of MuV PIV4a SV5 SV41 Paramyxovirinae hPIV2 Subfamily Rubulavirus NDV Avulavirus SalV hPIV3 CDV Mev SeV Morbillivirus Respirovirus Henipavirus TPMV Copyright 2006 Nature Publishing Group 8 Nature Reviews Microbiology 重庆医科大学儿童医院传染病教研室
8 ETIOLOGY MUMPS VIRUS MUMPS VIRUS Phylogenetic tree of Paramyxovirinae Subfamily
ETIOLOGY-MUMIPRERUISUS ■ Classification:A RNA virus single-stranded negative Genus:Rubulavirus Family:paramyxoviridae ■ Serotype:Only one Location:Saliva,Cerebrospinal fluid Blood,Urine,infectious tissues cold-resistant Disinfections:Rapidly inactivate by chemical agents,heat and ultraviolet light Man are only host 9 重庆医科大学儿童医院传染病教研室
9 ETIOLOGY MUMPS VIRUS ◼ Classification: A RNA virus single-stranded negative Genus: Rubulavirus Family: paramyxoviridae ◼ Serotype: Only one ◼ Location: Saliva, Cerebrospinal fluid Blood, Urine, infectious tissues ◼ cold-resistant ◼ Disinfections: Rapidly inactivate by chemical agents, heat and ultraviolet light ◼ Man are only host MUMPS VIRUS
ETIOLOGY一MMRIRJS Electron micrograph of the mumps virus 10 重庆医科大学儿童医院传染病教研室
10 ETIOLOGY MUMPS VIRUS Electron micrograph of the mumps virus MUMPS VIRUS