ORGANIC CHEMISTRY Chapter 16 16.6B Relative Reactivity: Aldehydes versus ketones 9 In general, aldehyde are more reactive in nucleophilic addition than are ketones C R H R R Aldehyde Ketone Carbonyl carbon is Carbonyl carbon is more positive less positive Department of Chemistry, Xiamen University
ORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 16 16.6B Relative Reactivity: Aldehydes versus Ketones In general, aldehyde are more reactive in nucleophilic addition than are ketones. R C H O δ+ δ− R C R O δ+ δ− Aldehyde Ketone Carbonyl carbon is more positive Carbonyl carbon is less positive
ORGANIC CHEMISTRY Chapter 16 16.6C Subsequent Reactions of Addition products R R-C-OH Nu o Nucleophilic Addition a c=0 may lead to a product that is stable under the reaction conditions that we employ o In other reactions the products formed initially may be unstable and may spontaneously undergo subsequent reactions(elimination reactions) Department of Chemistry, Xiamen University
ORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 16 16.6C Subsequent Reactions of Addition Products R R C OH Nu Nucleophilic Addition a C=O may lead to a product that is stable under the reaction conditions that we employ. In other reactions the products formed initially may be unstable and may spontaneously undergo subsequent reactions.(elimination reactions)
ORGANIC CHEMISTRY Chapter 16 16. 7 The addition of alcohols Hemiacetals and acetals 半缩醛(酮)和缩醛(酮) Department of Chemistry, Xiamen University
ORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 16 16.7 The Addition of Alcohols: Hemiacetals and Acetals 半缩醛（酮）和缩醛（酮）