4. Morphologic changes(1) Gross appearance:volumeweightl
4. Morphologic changes (1) Gross appearance: volume ↓ weight↓
Pressureatrophy ofkidney
Pressure atrophy of kidney
Pressure atrophy of brain6.17F1-44.JPG
Pressure atrophy of brain
(2)Histologicalchanges:Decreaseinthe sizeandnumberof cells.Lipofuscin → brown atrophy (heart or liver)Figure2-11Lipofuscin granules in a cardiac myocyte as shown by electron micros.copyLowmagnification.Notetheperinuclear.intralysosomal location
(2) Histological changes: Decrease in the size and number of cells. Lipofuscin → brown atrophy (heart or liver)
NormalmyocardiumAtrophy ofmyocardium
Atrophy of myocardium Normal myocardium