(一)Hypertrophy.Definition:an increase in the size of atissues or organ due to increasedsize of individual cells
（一）Hypertrophy 1. Definition: an increase in the size of a tissues or organ due to increased size of individual cells
2.Types(1) Physiologic hypertrophy:pregnancy → uterus↑(endocrine hypertrophy)
2.Types (1) Physiologic hypertrophy: pregnancy → uterus↑ (endocrine hypertrophy)
PhysiologichypertrophyofuterusFigure2-3Physiologic hypertrophyof the uterus during pregnancy.A,Gross appearance of a normal uterus (right)and a gravid uterus (removed for postpartumbleeding)(left).B,Small spindle-shapeduterine smoothmuscle cells from anormal uterus (left)compared with largeplump cells ingravid uterus (right)
Physiologic hypertrophy of uterus
(2)PathologichypertrophyHypertension → heart hypertrophyGN → residual nephron hypertrophy3.EMmitochondria ↑cellcomponentsendoplasmic reticulummicrofilamentprotein synthesis
(2) Pathologic hypertrophy Hypertension → heart hypertrophy GN → residual nephron hypertrophy 3. EM cell components mitochondria ↑ endoplasmic reticulum microfilament↑ protein synthesis↑
Myocardial hypertrophy图1-3心肌肥大心肌肥大图1-1图14心肌肥大（Mallory染色）图12正常心肌
Myocardial hypertrophy